User profiles for Antonella Cusimano
Antonella CusimanoIstituto per la Ricerca e l'Innovazione Biomedica (IRIB)-CNR Verified email at irib.cnr.it Cited by 1853 |
[HTML][HTML] Targeted therapy for hepatocellular carcinoma: novel agents on the horizon
Hepatocellular carcinoma (HCC) is the most common liver cancer, accounting for 90% of
primary liver cancers. In the last decade it has become one of the most frequently occurring …
primary liver cancers. In the last decade it has become one of the most frequently occurring …
Molecular mechanisms of sorafenib action in liver cancer cells
Sorafenib, a multikinase inhibitor, recently received FDA approval for the treatment of
advanced hepatocellular carcinoma (HCC). However, as the clinical application of sorafenib …
advanced hepatocellular carcinoma (HCC). However, as the clinical application of sorafenib …
Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti …
M Notarbartolo, M Cervello, L Dusonchet, A Cusimano… - Cancer letters, 2002 - Elsevier
We studied the human HL60 leukemia cell line and its multidrug resistant (MDR) variant
HL60R. In contrast to the HL60, HL60R showed an inability to undergo apoptosis from …
HL60R. In contrast to the HL60, HL60R showed an inability to undergo apoptosis from …
[PDF][PDF] Nanoalgosomes: Introducing extracellular vesicles produced by microalgae
…, C Paganini, M Gai, A Cusimano… - Journal of …, 2021 - Wiley Online Library
Cellular, inter‐organismal and cross kingdom communication via extracellular vesicles (EVs)
is intensively studied in basic science with high expectation for a large variety of bio‐…
is intensively studied in basic science with high expectation for a large variety of bio‐…
[HTML][HTML] Potential uses of olive oil secoiridoids for the prevention and treatment of cancer: a narrative review of preclinical studies
The Mediterranean diet (MD) is a combination of foods mainly rich in antioxidants and anti-inflammatory
nutrients that have been shown to have many health-enhancing effects. Extra-…
nutrients that have been shown to have many health-enhancing effects. Extra-…
[HTML][HTML] The role of GSK-3 in cancer immunotherapy: GSK-3 inhibitors as a new frontier in cancer treatment
G Augello, MR Emma, A Cusimano, A Azzolina… - Cells, 2020 - mdpi.com
The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified
because of its key role in the regulation of glycogen synthesis. However, it is now well-…
because of its key role in the regulation of glycogen synthesis. However, it is now well-…
[HTML][HTML] Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation
A Cusimano, D Balasus… - International …, 2017 - spandidos-publications.com
The beneficial health properties of the Mediterranean diet are well recognized. The principle
source of fat in Mediterranean diet is extra-virgin olive oil (EVOO). Oleocanthal (OC) is a …
source of fat in Mediterranean diet is extra-virgin olive oil (EVOO). Oleocanthal (OC) is a …
Isolation of extracellular vesicles from microalgae: towards the production of sustainable and natural nanocarriers of bioactive compounds
Safe, efficient and specific nano-delivery systems are essential for current and emerging
therapeutics, precision medicine and other biotechnology sectors. Novel bio-based …
therapeutics, precision medicine and other biotechnology sectors. Novel bio-based …
RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma
…, MR Emma, G Augello, A Cusimano… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Hepatocellular carcinoma (HCC) is a significant problem globally because of
viral infections and the increasing incidence of obesity and fatty liver disease. However, it is …
viral infections and the increasing incidence of obesity and fatty liver disease. However, it is …
Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX‐2 inhibitors
…, N D'ALESSANDRO, A Cusimano… - Annals of the New …, 2004 - Wiley Online Library
The aim of the present study was to examine the effects of nonselective (indomethacin) and
selective cyclooxygenase‐2 (COX‐2) inhibitors (NS‐398, nimesulide, and CAY10404) on …
selective cyclooxygenase‐2 (COX‐2) inhibitors (NS‐398, nimesulide, and CAY10404) on …