RNA-binding proteins (RBPs) are emerging as important effectors of the cellular DNA damage
response (DDR). The RBP FUS is implicated in RNA metabolism and DNA repair, and it …

In the last few years, the advent of new technological approaches has led to a better knowledge
of the ontogeny of erythropoiesis during development and of the journey leading from …

The expression of the fetal Gγ- and Aγ-globin genes in normal development is confined to
the fetal period, where two γ-globin chains assemble with two α-globin chains to form α 2 γ 2 …

Amyotrophic lateral sclerosis (ALS) is a relentless and fatal neurological disease characterized
by the selective degeneration of motor neurons. No effective therapy is available for this …

Naturally occurring nondeletional mutations affecting the distal CCAAT box of the human γ-globin
gene promoter result in hereditary persistence of fetal hemoglobin in adult life. …

SOX6 is a HMG-box transcription factor expressed in a wide range of tissues. Recent data
show that SOX6 expression is altered in different cancers, in the majority of cases being …

In this issue of Blood, Ludwig et al characterize a rare form of inherited hemolytic anemia.
They identified novel mutations in an intrinsically disordered region (IDR) in the GATA1 …

Nuclear receptors (NRs), are a wide family of ligand-regulated transcription factors sharing
a common modular structure composed by an N-terminal domain and a ligand-binding …

… e, LPS-induced cytokine production by BMDCs with and without soluble CD14 (2 μg ml -1
). b, c, d, e are representative of three experiments. Error bars in b–e represent standard errors…

RNA-binding proteins (RBPs) are emerging as important effectors of the cellular DNA damage
response (DDR). The RBP FUS is implicated in RNA metabolism and DNA repair, and it …