User profiles for Antonius Plagge

Antonius Plagge

Department of Biochemistry, Cell and Systems Biology, ISMIB, University of Liverpool
Verified email at liverpool.ac.uk
Cited by 1865

The imprinted signaling protein XLαs is required for postnatal adaptation to feeding

A Plagge, E Gordon, W Dean, R Boiani, S Cinti… - Nature …, 2004 - nature.com
Genomic imprinting, by which maternal and paternal alleles of some genes have different
levels of activity, has profound effects on growth and development of the mammalian fetus. The …

Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster

…, P Glenister, M Fray, Z Tymowska-Lalanne, A Plagge… - Nature …, 2006 - nature.com
Genomic imprinting results in allele-specific silencing according to parental origin 1 .
Silencing is brought about by imprinting control regions (ICRs) that are differentially marked in …

[PDF][PDF] Generation of functioning nephrons by implanting human pluripotent stem cell-derived kidney progenitors

…, D Forster, MC Asselin, P Lewis, R Lennon, A Plagge… - Stem cell reports, 2018 - cell.com
Human pluripotent stem cells (hPSCs) hold great promise for understanding kidney development
and disease. We reproducibly differentiated three genetically distinct wild-type hPSC …

A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas

…, ST Ball, WT Nottingham, JA Skinner, A Plagge… - Nature …, 2004 - nature.com
Genomic imprinting brings about allele-specific silencing according to parental origin 1 .
Silencing is controlled by cis-acting regulatory regions that are differentially marked during …

Physiological functions of the imprinted Gnas locus and its protein variants Galpha (s) and XLalpha (s) in human and mouse.

A Plagge, G Kelsey, EL Germain-Lee - The Journal of endocrinology, 2008 - europepmc.org
The stimulatory alpha-subunit of trimeric G-proteins Galpha (s), which upon ligand binding
to seven-transmembrane receptors activates adenylyl cyclases to produce the second …

Imprinted Nesp55 influences behavioral reactivity to novel environments

A Plagge, AR Isles, E Gordon, T Humby… - … and cellular biology, 2005 - Am Soc Microbiol
Genomic imprinting results in parent-of-origin-dependent monoallelic expression of selected
genes. Although their importance in development and physiology is recognized, few …

[HTML][HTML] The alternative stimulatory G protein α-subunit XLαs is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice

T Xie, A Plagge, O Gavrilova, S Pack, W Jou… - Journal of Biological …, 2006 - ASBMB
The complex imprinted Gnas locus encodes several gene products including G s α, the
ubiquitously expressed G protein α-subunit required for receptor-stimulated cAMP generation, …

[HTML][HTML] Firefly luciferase offers superior performance to AkaLuc for tracking the fate of administered cell therapies

F Amadeo, A Plagge, A Chacko, B Wilm… - European Journal of …, 2022 - Springer
Introduction A novel, red-shifted bioluminescence imaging (BLI) system called AkaBLI has
been recently developed for cell tracking in preclinical models and to date, limited data is …

[HTML][HTML] Multicolour in vivo bioluminescence imaging using a NanoLuc‐based BRET reporter in combination with firefly luciferase

A Taylor, J Sharkey, A Plagge, B Wilm… - Contrast Media & …, 2018 - hindawi.com
The ability to track the biodistribution and fate of multiple cell populations administered to
rodents has the potential to facilitate the understanding of biological processes in a range of …

Neurotractin, a novel neurite outgrowth-promoting Ig-like protein that interacts with CEPU-1 and LAMP

A Marg, P Sirim, F Spaltmann, A Plagge… - The Journal of cell …, 1999 - rupress.org
The formation of axon tracts in nervous system histogenesis is the result of selective axon
fasciculation and specific growth cone guidance in embryonic development. One group of …