Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …

Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Intelligence is associated with important economic and health-related life outcomes 1.
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic nature, …

The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …

Type 2 diabetes (T2D) is a common, polygenic chronic disease with high heritability. The
purpose of this whole-genome association study was to discover novel T2D-associated genes. …

Cognitive decline is a feared aspect of growing old. It is a major contributor to lower quality
of life and loss of independence in old age. We investigated the genetic contribution to …

Cannabinoid receptor 1 (CB1) gene (CNR1) knockout mice are prone to develop anhedonic
and helpless behavior after chronic mild stress. In humans, the CB1 antagonist rimonabant …

BACKGROUND: The neuroplastic pathway, which includes cyclic adenosine monophosphate
response element-binding protein 1 (CREB1), brain-derived neurotrophic factor (BDNF), …