User profiles for Antti Junkkari

Antti Junkkari

Helsinki University Hospital
Verified email at hus.fi
Cited by 302

Early Alzheimer's disease pathology in human cortex involves transient cell states

…, A Dougalis, SJ Burris, B Rooney, A Junkkari… - Cell, 2023 - cell.com
Cellular perturbations underlying Alzheimer's disease (AD) are primarily studied in human
postmortem samples and model organisms. Here, we generated a single-nucleus atlas from a …

[HTML][HTML] Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus

S Weiner, A Junkkari, M Sauer, A Luikku… - Fluids and Barriers of …, 2023 - Springer
Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult hydrocephalus
that is clinically characterized by progressive gait impairment, cognitive dysfunction, and …

Predicting development of Alzheimer's disease in patients with shunted idiopathic normal pressure hydrocephalus

…, S Helisalmi, SK Herukka, A Junkkari… - Journal of …, 2019 - content.iospress.com
Background: Idiopathic normal pressure hydrocephalus (iNPH) patients often develop
Alzheimer’s disease (AD) related brain pathology. Disease State Index (DSI) is a method to …

[HTML][HTML] Prevalence of schizophrenia in idiopathic normal pressure hydrocephalus

V Vanhala, A Junkkari, VE Korhonen, MI Kurki… - …, 2019 - journals.lww.com
BACKGROUND Idiopathic normal pressure hydrocephalus (iNPH) is a progressive and
potentially treatable neurodegenerative disease affecting elderly people, characterized by gait …

[HTML][HTML] Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states

…, T Kamath, NM Nadaf, SJ Burris, B Rooney, A Junkkari… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Cellular perturbations underlying Alzheimer’s disease are primarily studied in human postmortem
samples and model organisms. Here we generated a single-nucleus atlas from a rare …

Copy number loss in SFMBT1 is common among Finnish and Norwegian patients with iNPH

…, A Ronkainen, M Kauppinen, A Junkkari… - Neurology …, 2018 - AAN Enterprises
Objective To evaluate the role of the copy number loss in SFMBT1 in a Caucasian population.
Methods Five hundred sixty-seven Finnish and 377 Norwegian patients with idiopathic …

[HTML][HTML] Time trends of cerebrospinal fluid biomarkers of neurodegeneration in idiopathic normal pressure hydrocephalus

…, SK Herukka, VE Korhonen, A Junkkari… - Journal of …, 2021 - content.iospress.com
Background: Longitudinal changes in cerebrospinal fluid (CSF) biomarkers are seldom
studied. Furthermore, data on biomarker gradient between lumbar (L-) and ventricular (V-) …

The CERAD neuropsychological battery in patients with idiopathic normal pressure hydrocephalus compared with normal population and patients with mild …

O Nerg, A Junkkari, I Hallikainen… - Journal of …, 2021 - content.iospress.com
Background: The usefulness of CERAD Neuropsychological Battery for describing the cognitive
impairment in idiopathic normal pressure hydrocephalus (iNPH) is unknown. Objective: …

Antipsychotic use among 1144 patients after aneurysmal subarachnoid hemorrhage: a population-based case-control study

JT Paavola, N Väntti, A Junkkari, TJ Huttunen… - Stroke, 2019 - Am Heart Assoc
Background and Purpose— At acute phase and neurointensive care, patients with aneurysmal
subarachnoid hemorrhage (aSAH) may become agitated or delirious. We found no …

Utility of cortical tissue analysis in normal pressure hydrocephalus

…, E Kiziltug, PQ Duy, HR Smith, A Junkkari… - Cerebral …, 2024 - academic.oup.com
Clinical improvement following neurosurgical cerebrospinal fluid shunting for presumed
idiopathic normal pressure hydrocephalus is variable. Idiopathic normal pressure …