Hes-1 regulates the excitatory fate of neural progenitors through modulation of Tlx3 (HOX11L2) expression

…, VA Rasheed, SB Dhanesh, A Sebin… - Cellular and Molecular …, 2012 - Springer
Tlx3 (HOX11L2) is regarded as one of the selector genes in excitatory versus inhibitory fate
specification of neurons in distinct regions of the nervous system. Expression of Tlx3 in a post…

[HTML][HTML] The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1

…, PJ Batista, U Litzenburger, QY Lee, YH Ng, A Sebin… - Scientific Reports, 2022 - nature.com
The chromodomain helicase DNA-binding protein CHD8 is the most frequently mutated
gene in autism spectrum disorder. Despite its prominent disease involvement, little is known …

Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice

…, ES Coyne, X Ding, A Sebin… - American Journal …, 2022 - journals.physiology.org
Insulin resistance is a major public health burden that often results in other comorbidities
including type 2 diabetes, nonalcoholic fatty liver disease (NAFLD), and cardiovascular disease…

The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1

…, P Batista, U Litzenburger, QY Lee, YH Ng, A Sebin… - bioRxiv, 2020 - biorxiv.org
The chromodomain helicase DNA-binding protein CHD8 is among the most frequently found
de-novo mutations in autism ( 1 – 3 ). Unlike most other autism-risk genes, CHD8 mutations …

Competitive epidemic networks with multiple survival-of-the-fittest outcomes

M Ye, B Anderson, A Janson, S Gracy… - arXiv preprint arXiv …, 2021 - arxiv.org
We use a deterministic model to study two competing viruses spreading over a two-layer
network in the Susceptible--Infected--Susceptible (SIS) framework, and address a central …

Input-export fluxes of heavy metals in the Cochin estuary, southwest coast of India

KR Lallu, S John, KR Muraleedharan… - … Science and Pollution …, 2023 - Springer
Cochin estuary (CE) is one of the largest tropical estuaries along the southwest coast of India,
sustaining rich bio-resources. Several studies enlighten the environmental changes in the …

Competitive Networked Bivirus SIS spread over Hypergraphs

S Gracy, B Anderson, M Ye, CA Uribe - arXiv preprint arXiv:2309.14230, 2023 - arxiv.org
… Brian DO Anderson is with the School of Engineering, Australian National University, Canberra,
Australia. (brian.anderson@anu.edu.au) Mengbin Ye is with the Centre for Optimisation …

Analysis and distributed control of periodic epidemic processes

S Gracy, PE Paré, H Sandberg… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
This article studies epidemic processes over discrete-time periodic time-varying networks.
We focus on the susceptible-infected-susceptible (SIS) model that accounts for a (possibly) …

On the endemic behavior of a competitive tri-virus sis networked model

S Gracy, M Ye, BDO Anderson… - 2023 American Control …, 2023 - ieeexplore.ieee.org
We study the endemic behavior of a multi-competitive networked susceptible-infected-susceptible
(SIS) model. In particular, we focus on the case where there are three competing …

Disclosure of Diagnosis in Children with HIV: A Quantitative and Qualitative Analysis

SG Abraham - 2020 - repository-tnmgrmu.ac.in
Anu Rose helped me to frame the questionnaires for this study and was the moderator for
the focus group discussion. I thank her for her enthusiastic participation in the conduct of this …