p53 is primarily known as a downstream transcriptional effector in the DNA damage-response
cascade. We report that endogenous p53 rapidly accumulates at DNA damage sites …

The fluorescent probes having complete spectral separation between absorption and emission
spectra (large Stokes shift) are highly useful for solar concentrators and bioimaging. In …

Phosphoinositide lipids (PPIs) are enriched in the nucleus and are accumulated at DNA
damage sites. Here, we investigate roles of nuclear PPIs in DNA damage response by …

… Anushya Hariharan: developed western blots and performed PCR study and data analysis.
Yasaman Nematbakhsh: engineered stretching device. Bryant Lee Doss: performed AFM …

Mechanosensing is an integral part of many physiological processes including stem cell
differentiation, fibrosis, and cancer progression. Two major mechanosensing systems—focal …

Piezo1 is a mechanosensitive Ca2+-permeable channel that has been implicated in a
number of mechanosensing processes. It is diffusive on plasma membranes and activated by …

Ultrasound has been used to target tumors either through local heating or local nanobubbles
but these methods damage surrounding normal cells in the target area. Recent studies …

The structural characteristics of the seed‐mediated synthesis of heterostructured CuS–ZnS
nanocrystals (NCs) and Cu‐doped ZnS (ZnS:Cu) NCs synthesized by two different protocols …

Transformed cancer cells differ from normal cells in several important features like anchorage
independence, Warburg effect and mechanosensing. Consequently, transformed cancer …

Recent studies show that tumor cells undergo apoptosis after mechanical stretching that
promotes normal cell growth. Since ultrasound can produce similar sub-cellular mechanical …