User profiles for Aparna Ramachandran

Aparna Ramachandran, PhD

Rutgers - The State University of New Jersey
Verified email at rwjms.rutgers.edu
Cited by 795

A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2

…, D Bamming, A Komuro, A Ramachandran… - Journal of …, 2009 - Am Soc Microbiol
Diverse members of the Paramyxovirus family of negative-strand RNA viruses effectively
suppress host innate immune responses through the actions of their V proteins. The V protein …

STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition

A Ramachandran, JP Parisien, CM Horvath - Journal of virology, 2008 - Am Soc Microbiol
Measles virus, a member of the Morbillivirus family, infects millions of people each year
despite the availability of effective vaccines. The V protein of measles virus is an important …

Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation

A Ramachandran, U Basu, S Sultana… - Nucleic acids …, 2017 - academic.oup.com
Human mitochondrial DNA is transcribed by POLRMT with the help of two initiation factors,
TFAM and TFB2M. The current model postulates that the role of TFAM is to recruit POLRMT …

Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase

JG Bird, U Basu, D Kuster, A Ramachandran… - Elife, 2018 - elifesciences.org
10.7554/eLife.42179.001 Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap
RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine …

Implementation of an 8-core, 64-thread, power-efficient SPARC server on a chip

…, KC Yen, A Kumar, A Ramachandran… - IEEE Journal of Solid …, 2008 - ieeexplore.ieee.org
The second in the Niagara series of processors (Niagara2) from Sun Microsystems is based
on the power-efficient chip multi-threading (CMT) architecture optimized for Space, Watts (…

The use of virtual reality in the rehabilitation of aphasia: a systematic review

…, N Behn, J Marshall, A Ramachandran… - Disability and …, 2023 - Taylor & Francis
Purpose This systematic review explored how virtual reality (VR) has been used to rehabilitate
aphasia. Materials and methods Empirical studies were included where VR was used to …

Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference

A Ramachandran, CM Horvath - Journal of virology, 2010 - Am Soc Microbiol
The V protein of the paramyxovirus subfamily Paramyxovirinae is an important virulence
factor that can interfere with host innate immunity by inactivating the cytosolic pathogen …

Sequence-specific deoxyribonucleic acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for …

…, J Weck, Z Zhang, A Ramachandran… - Molecular …, 2006 - academic.oup.com
Steroidogenic factor 1 (SF1) is a member of the NR5A subfamily of nuclear hormone receptors
and is considered a master regulator of reproduction because it regulates a number of …

Paramyxovirus disruption of interferon signal transduction: STATus report

A Ramachandran, CM Horvath - Journal of Interferon & Cytokine …, 2009 - liebertpub.com
RNA viruses in the paramyxovirus family have evolved a number of strategies to escape host
cell surveillance and antiviral responses. One mechanism exploited by a number of viruses …

Prevalence, nature, and severity of the psychiatric comorbidities and their impact on quality of life in adolescents with Juvenile myoclonic epilepsy

PK Panda, A Ramachandran, A Tomar, A Elwadhi… - Epilepsy & Behavior, 2023 - Elsevier
Introduction Adults with Juvenile myoclonic epilepsy (JME) are at increased risk for psychiatric
comorbidities, personality traits, and abnormality in executive function. But studies on …