Relaxases play essential roles in conjugation, the main process by which bacteria exchange
genetic material, notably antibiotic resistance genes. They are bifunctional enzymes …

Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS),
a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-…

Conjugation is one of the most important processes that bacteria utilize to spread antibiotic
resistance genes among bacterial populations. Interbacterial DNA transfer requires a large …

Conjugation, the process by which plasmid DNA is transferred from one bacterium to another,
is mediated by type IV secretion systems (T4SSs). T4SSs are versatile systems that can …

Conjugative pili are widespread bacterial appendages that play important roles in horizontal
gene transfer, in spread of antibiotic resistance genes, and as sites of phage attachment. …

Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from
one bacterium to another during conjugation. They covalently react with a specific …

Genome duplication is essential for the proliferation of cellular life and this process is
generally initiated by dedicated replication proteins at chromosome origins. In bacteria, DNA …

Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic Escherichia coli (EHEC)
utilize a macromolecular type III secretion system (T3SS) to inject effector proteins into …

Bidirectional DNA replication from a chromosome origin requires the asymmetric loading of
two helicases, one for each replisome. Our understanding of the molecular mechanisms …

Genome replication is a fundamental biological activity shared by all organisms. Chromosomal
replication proceeds bidirectionally from origins, requiring the loading of two helicases, …