Cyclooxygenase-2 (Cox-2) expression can induce mammary tumorigenesis in transgenic
mice, and selective Cox-2 inhibitors are both chemopreventive and chemotherapeutic in rat …

Epidemiological studies suggest that the use of aspirin decreases the incidence of and
mortality from gastrointestinal cancers. The best known target of aspirin and other nonsteroidal …

Epidemiological studies indicate that the use of aspirin decreases incidence of and mortality
from gastrointestinal cancers. A major target of aspirin and other nonsteroid anti-…

Tumor budding is a well-established independent prognostic factor in colorectal cancer but
a standardized method for its assessment has been lacking. The primary aim of the …

The vascular endothelial growth factor (VEGF) family has recently been expanded by the
isolation of two additional growth factors, VEGF-B and VEGF-C. Here we compare the …

Homozygosity for the G allele of rs6983267 at 8q24 increases colorectal cancer (CRC) risk
∼1.5 fold. We report here that the risk allele G shows copy number increase during CRC …

Vascular endothelial growth factor (VEGF) is a prime regulator of normal and pathological
angiogenesis. Three related endothelial cell growth factors, VEGF-B, VEGF-C, and VEGF-D …

The tumour suppressor APC is the most commonly mutated gene in colorectal cancer. Loss
of Apc in intestinal stem cells drives the formation of adenomas in mice via increased WNT …

VEGF-C is a recently characterised endothelial growth factor structurally related to vascular
endothelial growth factor (VEGF). We studied the expression of VEGF-C and VEGF in the …

Ameloblastoma is a benign but locally infiltrative odontogenic neoplasm. Although
ameloblastomas rarely metastasise, recurrences together with radical surgery often result in facial …