Melanocortin 4 receptor mutations contribute to the adaptation of cavefish to nutrient-poor conditions

AC Aspiras, N Rohner, B Martineau… - Proceedings of the …, 2015 - National Acad Sciences
Despite recent advances in the understanding of morphological evolution, the genetic
underpinnings of behavioral and physiological evolution remain largely unknown. Here, we study …

Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

MR Riddle, AC Aspiras, K Gaudenz, R Peuß, JY Sung… - Nature, 2018 - nature.com
Periodic food shortages are a major challenge faced by organisms in natural habitats. Cave-dwelling
animals must withstand long periods of nutrient deprivation, as—in the absence of …

A relative shift in cloacal location repositions external genitalia in amniote evolution

…, E Sherratt, TJ Sanger, AC Groner, AC Aspiras… - Nature, 2014 - nature.com
The move of vertebrates to a terrestrial lifestyle required major adaptations in their
locomotory apparatus and reproductive organs. While the fin-to-limb transition has received …

Collective behavior emerges from genetically controlled simple behavioral motifs in zebrafish

R Harpaz, AC Aspiras, S Chambule, S Tseng… - Science …, 2021 - science.org
It is not understood how changes in the genetic makeup of individuals alter the behavior of
groups of animals. Here, we find that, even at early larval stages, zebrafish regulate their …

[HTML][HTML] Sex-specific gene interactions in the patterning of insect genitalia

AC Aspiras, FW Smith, DR Angelini - Developmental Biology, 2011 - Elsevier
Genitalia play an important role in the life histories of insects, as in other animals. These
sexually dimorphic structures evolve rapidly and derive from multiple body segments. Despite …

Patterning of the Adult Mandibulate Mouthparts in the Red Flour Beetle, Tribolium castaneum

DR Angelini, FW Smith, AC Aspiras, M Kikuchi… - Genetics, 2012 - academic.oup.com
Specialized insect mouthparts, such as those of Drosophila, are derived from an ancestral
mandibulate state, but little is known about the developmental genetics of mandibulate …

Genetic architecture underlying changes in carotenoid accumulation during the evolution of the blind Mexican cavefish, Astyanax mexicanus

MR Riddle, AC Aspiras, F Damen… - … Zoology Part B …, 2020 - Wiley Online Library
Carotenoids are lipid‐soluble yellow to orange pigments produced by plants, bacteria, and
fungi. They are consumed by animals and metabolized to produce molecules essential for …

Collective behavior emerges from genetically controlled simple behavioral motifs in zebrafish

AC Aspiras, R Harpaz, S Chambule, S Tseng, F Engert… - bioRxiv, 2021 - biorxiv.org
Since Darwin, coordinated movement of animal groups has been believed to be essential to
species survival, but it is not understood how changes in the genetic makeup of individuals …

Author Correction: Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

MR Riddle, AC Aspiras, K Gaudenz, R Peuß, JY Sung… - Nature, 2020 - nature.com
Cave-adapted populations of the Mexican tetra, Astyanax mexicanus, have dysregulated
blood glucose homeostasis and are insulin-resistant compared to river-adapted (‘surface’) …

Sex-specific gene interactions in the patterning of Oncopeltus fasciatus genitalia

AC Aspiras - 2012 - aura.american.edu
Genitalia play an important role in the life histories of insects, as in other animals. These
structures are a unique developmental system to explore as they are rapidly evolving sexually …