Cystic fibrosis–related (CF-related) diabetes (CFRD) is an increasingly common and
devastating comorbidity of CF, affecting approximately 35% of adults with CF. However, the …

Glycosylation plays important roles in cellular function and endows protein therapeutics with
beneficial properties. However, constructing biosynthetic pathways to study and engineer …

Vaccines against COVID-19 have the potential to protect people before they are exposed to
the infective form of the virus. However, because of the involvement of pathogenic immune …

Introduction Current and developing mast cell therapeutics are reliant on small molecule
drugs and biologics, but few are truly selective for mast cells. Most have cellular and disease-…

… for 20 h at room temperature, with the exception of LgtB, which was flash frozen after 6 h
to … IVG assemblies were incubated at 30 C for 24 h, at which time sugar substrates were …

In resource-limited settings, it can be difficult to safely deliver sensitive biologic medicines to
patients due to cold chain and infrastructure constraints. Point-of-care drug manufacturing …

Allergens are used in the clinical diagnosis (eg, skin tests) and treatment (eg, immunotherapy)
of allergic diseases. With growing interest in molecular allergy diagnostics and precision …

In resource-limited settings, it can be difficult to safely deliver sensitive biologic medicines to
patients due to cold chain and infrastructure constraints. Point-of-care drug manufacturing …

Objectives This paper synthesizes the effects on repeat offending reported in ten eligible
randomized trials of face-to-face restorative justice conferences (RJCs) between crime victims, …

Purpose What is the effect of having a criminal record compared to having the criminal
record expunged in exchange for participating in a rehabilitative programme? The available …