Microbiota have emerged as key modulators of both the carcinogenic process and the
immune response against cancer cells, and, thus, it seems to influence the efficacy of …

El veneno del alacrán azul, Rophalurus junceus es comercializado con el nombre de Escozul.
Este producto natural se emplea en el tratamiento de diferentes patologías. OBJETIVO: …

NK cells are key mediators of immune cell-mediated cytotoxicity toward infected and
transformed cells, being one of the main executors of cell death in the immune system. NK cells …

The proteasome inhibitor bortezomib is now the cornerstone of combination therapy of
multiple myeloma (MM). Carfilzomib, a second-generation inhibitor, has shown a substantial …

Immune checkpoint receptors (IC) positively or negatively regulate the activation of the host
immune response, preventing unwanted reactions against self-healthy tissues. In recent …

If not properly regulated, the inflammatory immune response can promote carcinogenesis,
as evident in colorectal cancer (CRC). Aiming to gain mechanistic insight into the link …

The advances in molecular biology and the emergence of Next Generation Sequencing (NGS)
have revealed that microbiome composition is closely related with health and disease, …

Deficiency in DNA double-strand break (DSB) repair mechanisms has been widely
exploited for the treatment of different malignances, including homologous recombination (HR)-…

Simple Summary In recent years, studies in cancer immunotherapy have focused on finding
predictive response biomarkers to anticipate which patients will respond to each kind of …

Granulysin is a protein present in the granules of human CTL and NK cells, with cytolytic
activity against microbes and tumors. Previous work demonstrated that granulysin caused cell …