User profiles for Aritoshi Iida
Aritoshi IidaMedical Genome Center, NCNP, Tokyo Verified email at ncnp.go.jp Cited by 9203 |
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
…, S Wakitani, R Teshima, Y Nishioka, A Sekine, A Iida… - Nature …, 2003 - nature.com
Individuals with rheumatoid arthritis frequently have autoantibodies to citrullinated peptides,
suggesting the involvement of the peptidylarginine deiminases citrullinating enzymes (…
suggesting the involvement of the peptidylarginine deiminases citrullinating enzymes (…
Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction
By means of a large-scale, case-control association study using 92,788 gene-based single-nucleotide
polymorphism (SNP) markers, we identified a candidate locus on chromosome …
polymorphism (SNP) markers, we identified a candidate locus on chromosome …
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
…, T Ichimori, S Saito, A Sekine, A Iida… - Human molecular …, 2005 - academic.oup.com
The inflammatory bowel diseases (IBDs), Crohn's disease (CD) and ulcerative colitis, are
chronic inflammatory disorders of the digestive tract. The pathogenesis of IBD is complicated, …
chronic inflammatory disorders of the digestive tract. The pathogenesis of IBD is complicated, …
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
H Kizawa, I Kou, A Iida, A Sudo, Y Miyamoto… - Nature …, 2005 - nature.com
Osteoarthritis is the most common form of human arthritis. We investigated the potential role
of asporin, an extracellular matrix component expressed abundantly in the articular cartilage …
of asporin, an extracellular matrix component expressed abundantly in the articular cartilage …
Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro
K Ozaki, K Inoue, H Sato, A Iida, Y Ohnishi, A Sekine… - Nature, 2004 - nature.com
Myocardial infarction (MI) has become one of the leading causes of death in the world. Its
pathogenesis includes chronic formation of plaque inside the vessel wall of the coronary artery …
pathogenesis includes chronic formation of plaque inside the vessel wall of the coronary artery …
[PDF][PDF] Expansion of GGC repeat in GIPC1 is associated with oculopharyngodistal myopathy
…, T Sato, S Ura, Y Oya, M Ogasawara, A Iida… - The American Journal of …, 2020 - cell.com
Oculopharyngodistal myopathy (OPDM) is an adult-onset inherited neuromuscular disorder
characterized by progressive ptosis, external ophthalmoplegia, and weakness of the …
characterized by progressive ptosis, external ophthalmoplegia, and weakness of the …
[PDF][PDF] A functional SNP in BNC2 is associated with adolescent idiopathic scoliosis
…, K Watanabe, N Hosogane, E Okada, A Iida… - The American Journal of …, 2015 - cell.com
Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity. We previously
conducted a genome-wide association study (GWAS) and detected two loci associated with AIS…
conducted a genome-wide association study (GWAS) and detected two loci associated with AIS…
[PDF][PDF] Mutations in B3GALT6, which encodes a glycosaminoglycan linker region enzyme, cause a spectrum of skeletal and connective tissue disorders
…, S Mizumoto, N Miyake, R Kogawa, A Iida… - The American Journal of …, 2013 - cell.com
Proteoglycans (PGs) are a major component of the extracellular matrix in many tissues and
function as structural and regulatory molecules. PGs are composed of core proteins and …
function as structural and regulatory molecules. PGs are composed of core proteins and …
[HTML][HTML] CGG expansion in NOTCH2NLC is associated with oculopharyngodistal myopathy with neurological manifestations
M Ogasawara, A Iida, T Kumutpongpanich… - Acta Neuropathologica …, 2020 - Springer
Oculopharyngodistal myopathy (OPDM) is a rare hereditary muscle disease characterized
by progressive distal limb weakness, ptosis, ophthalmoplegia, bulbar muscle weakness and …
by progressive distal limb weakness, ptosis, ophthalmoplegia, bulbar muscle weakness and …
[PDF][PDF] Citrullination of RGG motifs in FET proteins by PAD4 regulates protein aggregation and ALS susceptibility
Recent proteome analyses have provided a comprehensive overview of various posttranslational
modifications (PTMs); however, PTMs involving protein citrullination remain unclear. …
modifications (PTMs); however, PTMs involving protein citrullination remain unclear. …