Understanding multicellular function and disease with human tissue-specific networks
Tissue and cell-type identity lie at the core of human physiology and disease. Understanding
the genetic underpinnings of complex tissues and individual cell lineages is crucial for …
the genetic underpinnings of complex tissues and individual cell lineages is crucial for …
Molecular and physiological analysis of drought stress in Arabidopsis reveals early responses leading to acclimation in plant growth
A Harb, A Krishnan, MMR Ambavaram… - Plant physiology, 2010 - academic.oup.com
Plant drought stress response and resistance are complex biological processes that need to
be analyzed at a systems level using genomics and physiological approaches to dissect …
be analyzed at a systems level using genomics and physiological approaches to dissect …
Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene
…, N Marsch-Martinez, A Krishnan… - Proceedings of the …, 2007 - National Acad Sciences
Freshwater is a limited and dwindling global resource; therefore, efficient water use is
required for food crops that have high water demands, such as rice, or for the production of …
required for food crops that have high water demands, such as rice, or for the production of …
Effects of drought on gene expression in maize reproductive and leaf meristem tissue revealed by RNA-Seq
…, MMR Ambavaram, C Klumas, A Krishnan… - Plant …, 2012 - academic.oup.com
Drought stress affects cereals especially during the reproductive stage. The maize (Zea
mays) drought transcriptome was studied using RNA-Seq analysis to compare drought-treated …
mays) drought transcriptome was studied using RNA-Seq analysis to compare drought-treated …
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a strong
genetic basis. Yet, only a small fraction of potentially causal genes—about 65 genes out of an …
genetic basis. Yet, only a small fraction of potentially causal genes—about 65 genes out of an …
[HTML][HTML] Coordinated regulation of photosynthesis in rice increases yield and tolerance to environmental stress
MMR Ambavaram, S Basu, A Krishnan… - Nature …, 2014 - nature.com
Plants capture solar energy and atmospheric carbon dioxide (CO 2 ) through photosynthesis,
which is the primary component of crop yield, and needs to be increased considerably to …
which is the primary component of crop yield, and needs to be increased considerably to …
Coordinated activation of cellulose and repression of lignin biosynthesis pathways in rice
MMR Ambavaram, A Krishnan, KR Trijatmiko… - Plant …, 2011 - academic.oup.com
Cellulose from plant biomass is the largest renewable energy resource of carbon fixed from
the atmosphere, which can be converted into fermentable sugars for production into ethanol. …
the atmosphere, which can be converted into fermentable sugars for production into ethanol. …
Mutant resources in rice for functional genomics of the grasses
Rice (Oryza sativa) is the reference genome for the grasses, including cereals. The complete
genome sequence lays the foundation for comparative genomics to the other grasses …
genome sequence lays the foundation for comparative genomics to the other grasses …
[HTML][HTML] Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants
Purpose To assess the contribution of rare variants in the genetic background toward variability
of neurodevelopmental phenotypes in individuals with rare copy-number variants (CNVs…
of neurodevelopmental phenotypes in individuals with rare copy-number variants (CNVs…
Targeted exploration and analysis of large cross-platform human transcriptomic compendia
We present SEEK (search-based exploration of expression compendia; http://seek.princeton.edu/
), a query-based search engine for very large transcriptomic data collections, including …
), a query-based search engine for very large transcriptomic data collections, including …