User profiles for Arnab Mutsuddy

Arnab Mutsuddy

Clemson University
Verified email at g.clemson.edu
Cited by 11

[HTML][HTML] A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling

C Erdem, A Mutsuddy, EM Bensman, WB Dodd… - Nature …, 2022 - nature.com
Mechanistic models of how single cells respond to different perturbations can help integrate
disparate big data sets or predict response to varied drug combinations. However, the …

Computational speed-up of large-scale, single-cell model simulations via a fully integrated SBML-based format

A Mutsuddy, C Erdem, JR Huggins… - Bioinformatics …, 2023 - academic.oup.com
Arnab Mutsuddy … The authors wish it to be known that, in their opinion, Arnab Mutsuddy
and Cemal … The authors wish it to be known that, in their opinion, Arnab Mutsuddy and Cemal …

[PDF][PDF] A Simple and Efficient Pipeline for Construction, Merging, Expansion, and Simulation of Large-Scale, Single-Cell Mechanistic Models

C Erdem, EM Bensman, A Mutsuddy… - bioRxiv, 2020 - scholar.archive.org
The current era of big biomedical data accumulation and availability brings data integration
opportunities for leveraging its totality to make new discoveries and/or clinically predictive …

Good practices for building dynamical models in systems biology

EU Azeloglu, R Iyengar - Science signaling, 2015 - science.org
Dynamic models can offer deep understanding of information processing mechanisms in
physiology, cell signaling, and biological regulation when they are appropriately detailed. Here…

Fluorescence Multiplexing with Combination Probes for Biological and Diagnostic Applications

M McCarthy - 2023 - search.proquest.com
Cancer refers to a group of diseases containing more than 200 different subtypes. Cancer is
a heterogeneous disease by nature, meaning that there are differences among tumors of …

Integrating network reconstruction with mechanistic modeling to predict cancer therapies

M Halasz, BN Kholodenko, W Kolch, T Santra - Science signaling, 2016 - science.org
Signal transduction networks are often rewired in cancer cells. Identifying these alterations
will enable more effective cancer treatment. We developed a computational framework that …