Cytoplasmic dynein-1 binds dynactin and cargo adaptor proteins to form a transport machine
capable of long-distance processive movement along microtubules. However, it is unclear …

10.7554/eLife.23352.001 Centromeres are unique chromosomal loci that promote the
assembly of kinetochores, macromolecular complexes that bind spindle microtubules during …

The dynamic regulation of microtubules (MTs) during mitosis is critical for accurate chromosome
segregation and genome stability. Cancer cell lines with hyperstabilized kinetochore …

Type II secretion systems (T2SSs) generally release their substrates into the culture medium.
A few T2SS substrates remain anchored to or bound at the surface of the bacteria after …

Clathrin ensures mitotic spindle stability and efficient chromosome alignment, independently
of its vesicle trafficking function. Although clathrin localizes to the mitotic spindle and …

c‐Type cytochromes require specific post‐translational protein systems, which vary in
different organisms, for the characteristic covalent attachment of heme to the cytochrome …

The twin arginine translocation (Tat) pathway exports folded proteins from the cytoplasm to
the periplasm of bacteria. The targeting of the exported proteins to the Tat pathway relies on a …

Bacterial artificial chromosome (BAC)-based transgenes have emerged as a powerful tool
for controlled and conditional interrogation of protein function in higher eukaryotes. While …

Le système Tat (pour Twin Arginine Translocation) exporte des protéines repliées depuis le
cytoplasme vers le périplasme des bactéries. L’adressage des protéines à exporter au …

Bacterial artificial chromosome (BAC)–based transgenes have emerged as a powerful tool
for controlled and conditional interrogation of protein function in higher eukaryotes. Although …