The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific
fourth vertebrate whole-genome duplication, Ss4R) provides unique …

A fundamental goal in biology is to achieve a mechanistic understanding of how and to
what extent ecological variation imposes selection for distinct traits and favors the fixation of …

The number of chromosome sets contained within the nucleus of eukaryotic organisms is a
fundamental yet evolutionarily poorly characterized genetic variable of life. Here, we mapped …

… AB Gjuvsland and JO Vik contributed equally to this paper. … [ Arne B. Gjuvsland is a researcher
at the Centre for Integrative Genetics at the Norwegian University of Life Sciences. He did …

Functional dependencies between genes are a defining characteristic of gene networks
underlying quantitative traits. However, recent studies show that the proportion of the genetic …

Background Sequence-based genome-wide association studies (GWAS) provide high
statistical power to identify candidate causal mutations when a large number of individuals with …

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals,
reducing fertility. Especially in small size domestic and wild populations, those alleles might …

A fundamental question in biology is whether variation in organisms primarily emerges as a
function of adaptation or as a function of neutral genetic drift. Trait variation in the model …

Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before
returning to spawn in freshwater. The transition to marine habitats is associated with dramatic …

Background Deterministic dynamic models of complex biological systems contain a large
number of parameters and state variables, related through nonlinear differential equations with …