Background Women with gestational diabetes are at increased risk of developing type 2
diabetes, but the risk and time of onset have not been fully quantified. We therefore did a …

Objective To quantify the risk of future cardiovascular diseases, cancer, and mortality after
pre-eclampsia. Design Systematic review and meta-analysis. Data sources Embase and …

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …

Genetic association studies, in particular the genome-wide association study (GWAS)
design, have provided a wealth of novel insights into the aetiology of a wide range of human …

Background Systemic inflammation may impair vascular function, and epidemiologic data
suggest a possible link between periodontitis and cardiovascular disease. Methods We …

The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and …

Background A consensus has emerged that angiotensin-converting-enzyme (ACE)
inhibitors and angiotensin-II receptor blockers (ARBs) have specific renoprotective effects. …

Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …