[HTML][HTML] High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children

AW Kamng'ona, J Hinds, N Bar-Zeev, KA Gould… - BMC infectious …, 2015 - Springer
Background Carriage of either single or multiple pneumococcal serotypes (multiple carriage)
is a prerequisite for developing invasive pneumococcal disease. However, despite the …

[HTML][HTML] High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

…, A Gori, N Bar-Zeev, D Everett, AW Kamng'ona… - Nature …, 2020 - nature.com
There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa
sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and …

Recombination in Streptococcus pneumoniae lineages increase with carriage duration and size of the polysaccharide capsule

…, JE Cornick, M Yang, L Bricio-Moreno, AW Kamng'ona… - MBio, 2016 - Am Soc Microbiol
Streptococcus pneumoniae causes a high burden of invasive pneumococcal disease (IPD)
globally, especially in children from resource-poor settings. Like many bacteria, the …

[HTML][HTML] Provision of lipid-based nutrient supplements to mothers during pregnancy and 6 months postpartum and to their infants from 6 to 18 months promotes infant …

W Kamng'ona Arox, Y Rebecca, P Noel, K Emma… - The Journal of …, 2020 - Elsevier
Background: Diet may alter the configuration of gut microbiota, but the impact of prenatal
and postnatal nutritional interventions on infant gut microbiota has not been investigated. …

[HTML][HTML] The association of gut microbiota characteristics in Malawian infants with growth and inflammation

AW Kamng'ona, R Young, CD Arnold, E Kortekangas… - Scientific reports, 2019 - nature.com
We tested the hypotheses that a more mature or diverse gut microbiota will be positively
associated with infant growth and inversely associated with inflammation. We characterized gut …

[HTML][HTML] Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi

…, P Musicha, C Peno, N Bar-Zeev, AW Kamng'ona… - Vaccine, 2017 - Elsevier
Introduction Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA)
but the recently rolled out pneumococcal conjugate vaccines (PCV) will reduce the disease …

[HTML][HTML] Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines

…, IT Shawa, K Barnes, AW Kamng'ona… - Vaccines, 2022 - mdpi.com
Following the introduction of live-attenuated rotavirus vaccines in many countries, a notable
reduction in deaths and hospitalisations associated with diarrhoea in children <5 years of …

Rotavirus genotypes in hospitalized children with acute gastroenteritis before and after rotavirus vaccine introduction in Blantyre, Malawi, 1997–2019

…, UD Parashar, VE Pitzer, AW Kamng'ona… - The Journal of …, 2022 - academic.oup.com
Background Rotavirus vaccine (Rotarix [RV1]) has reduced diarrhea-associated hospitalizations
and deaths in Malawi. We examined the trends in circulating rotavirus genotypes in …

Gut microbiota-mediated pesticide toxicity in humans: Methodological issues and challenges in the risk assessment of pesticides

W Utembe, AW Kamng'ona - Chemosphere, 2021 - Elsevier
… Author links open overlay panel Wells Utembe a b , Arox Wadson Kamngona c d … to high
infant gut microbiota diversity at 18 months of age (Kamngona et al., 2020). Genetic factors as …

Environmental exposures and child and maternal gut microbiota in rural Malawi

E Kortekangas, AW Kamng'ona, YM Fan… - Paediatric and …, 2020 - Wiley Online Library
Background Gut microbiota composition is associated with child health, but the effect of the
environment on microbiota composition is not well understood. Few studies have been …