Clinical and cost-effectiveness of compression hosiery versus compression bandages in treatment of venous leg ulcers (Venous leg Ulcer Study IV, VenUS IV): a …
Background Drawbacks exist with the standard treatment (four-layer compression bandages)
for venous leg ulcers. We have therefore compared the clinical effectiveness and cost-…
for venous leg ulcers. We have therefore compared the clinical effectiveness and cost-…
[HTML][HTML] VenUS IV (Venous leg Ulcer Study IV)-compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised …
…, JC Dumville, CP Iglesias, AR Kang'ombe… - Health technology …, 2014 - ncbi.nlm.nih.gov
BACKGROUND Compression is an effective and recommended treatment for venous leg
ulcers. Although the four-layer bandage (4LB) is regarded as the gold standard compression …
ulcers. Although the four-layer bandage (4LB) is regarded as the gold standard compression …
[HTML][HTML] Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort
…, JK Simpson, AR Kang'ombe, R Braybrooke… - Respiratory …, 2019 - Springer
Idiopathic pulmonary fibrosis (IPF) is characterised by excessive extracellular matrix (ECM)
deposition and remodelling. Measuring this activity provides an opportunity to develop tools …
deposition and remodelling. Measuring this activity provides an opportunity to develop tools …
[HTML][HTML] A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose …
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with
poor prognosis and a significant unmet medical need. This study evaluated the safety, …
poor prognosis and a significant unmet medical need. This study evaluated the safety, …
[HTML][HTML] Validation of the VEINES-QOL quality of life instrument in venous leg ulcers: repeatability and validity study embedded in a randomised clinical trial
…, R Gabe, N Stubbs, U Adderley, AR Kang'ombe… - BMC cardiovascular …, 2015 - Springer
Background VEINES-QOL/Sym is a disease-specific quality of life instrument for use in venous
diseases of the leg. Its relative scoring system precludes comparisons between studies. …
diseases of the leg. Its relative scoring system precludes comparisons between studies. …
[HTML][HTML] Clinical quantification of the integrin αvβ6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study)
…, M Costa, S Kendrick, M Onega, AR Kang'ombe… - European Journal of …, 2020 - Springer
Purpose The RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis
through activation of transforming growth factor beta (TGFβ). This study sought to quantify …
through activation of transforming growth factor beta (TGFβ). This study sought to quantify …
Human immunodeficiency virus and risk of type 2 diabetes in a large adult cohort in Jos, Nigeria
Background. Human immunodeficiency virus (HIV) infection and the use of antiretroviral
therapy (ART) may increase the risk of type 2 diabetes mellitus (T2DM). However, data from …
therapy (ART) may increase the risk of type 2 diabetes mellitus (T2DM). However, data from …
Use of weekly, low dose, high frequency ultrasound for hard to heal venous leg ulcers: the VenUS III randomised controlled trial
Objective To assess the clinical effectiveness of weekly delivery of low dose, high frequency
therapeutic ultrasound in conjunction with standard care for hard to heal venous leg ulcers. …
therapeutic ultrasound in conjunction with standard care for hard to heal venous leg ulcers. …
Hypertension in treated and untreated patients with HIV: a study from 2011 to 2013 at the Jos University Teaching Hospital, Nigeria
SE Isa, AR Kang'ombe, GS Simji… - Transactions of the …, 2017 - academic.oup.com
Background Individuals with HIV, especially those on antiretroviral therapy (ART), may have
increased risk of hypertension. We investigated the prevalence of hypertension at enrolment …
increased risk of hypertension. We investigated the prevalence of hypertension at enrolment …
Conceptual, design, and statistical complications associated with participant preference
…, DJ Torgerson, AR Kang'Ombe - The Annals of the …, 2010 - journals.sagepub.com
… Arthur R. Kang’ombe is a biostatistician working with the Health Sciences Department, York
Trials Unit, at the University of York. He has a methodological interest in survival data, mixed …
Trials Unit, at the University of York. He has a methodological interest in survival data, mixed …