Bacterial type IV secretion systems (T4SSs) can function to export or import DNA, and can
deliver effector proteins into a wide range of target cells. Relatively little is known about the …

10.7554/eLife.47644.001 Bacterial type IV secretion systems (T4SSs) are molecular machines
that can mediate interbacterial DNA transfer through conjugation and delivery of effector …

Helicobacter pylori colonizes about half of humans worldwide, and its presence in the gastric
mucosa is associated with an increased risk of gastric adenocarcinoma, gastric lymphoma, …

10.7554/eLife.49748.001 Uropathogenic Escherichia coli (UPEC) is the major causative
agent of uncomplicated urinary tract infections (UTIs). A common virulence genotype of UPEC …

Uropathogenic Escherichia coli (UPEC) is the primary causative agent of uncomplicated
urinary tract infections (UTIs). UPEC fitness and virulence determinants have been evaluated in …

Urinary tract infections (UTI) account for a substantial financial burden globally. Over 75% of
UTIs are caused by uropathogenic Escherichia coli (UPEC), which have demonstrated an …

Helicobacter pylori colonizes the stomach in about half of the world’s population. H. pylori
strains containing the cag pathogenicity island (cag PAI) are associated with a higher risk of …

Helicobacter pylori colonizes the human stomach and confers an increased risk for the
development of peptic ulceration, noncardia gastric adenocarcinoma, and gastric lymphoma. A …

More than half of women will experience a urinary tract infection (UTI), with uropathogenic
Escherichia coli (UPEC) causing ~80% of uncomplicated cases. Iron acquisition systems are …

Helicobacter pylori colonizes the gastric mucosa and secretes a pore-forming toxin (VacA).
Two main types of VacA, m1 and m2, can be distinguished by phylogenetic analysis. Type …