Sulfated glycosaminoglycans (GAGs) are a class of important biologics that are currently
manufactured by extraction from animal tissues. Although such methods are unsustainable and …

The northern limits of three mangrove species—Avicennia germinans (Black Mangrove),
Rhizophora mangle (Red Mangrove), Laguncularia racemosa (White Mangrove)—on the …

Heparin is a highly sulfated, complex polysaccharide and widely used anticoagulant
pharmaceutical. In this work, we chemoenzymatically synthesized perdeuteroheparin from …

Cell-free protein synthesis systems that can be lyophilized for long-term, non-refrigerated
storage and transportation have the potential to enable decentralized biomanufacturing. …

Cell therapy for the injured spinal cord will rely on combined advances in human stem cell
technologies and delivery strategies. Here we encapsulate homotypic spinal cord neural stem …

… Author links open overlay panel Abinaya Badri 1 , Asher Williams 1 , Robert J Linhardt 1
2 3 , Mattheos AG Koffas 1 3 … Williams, JS Dordick, MAG Koffas, RJ Linhardt …

Heparin is an anionic polysaccharide that is widely used as a clinical anticoagulant. This
glycosaminoglycan is prepared from animal tissues in metric ton quantities. Animal‐sourced …

Chondroitin sulfates (CSs) are linear glycosaminoglycans that have important applications
in the medical and food industries. Engineering bacteria for the microbial production of CS …

Background Heparosan is the unsulfated precursor of heparin and heparan sulfate and its
synthesis is typically the first step in the production of bioengineered heparin. In addition to its …

Vaccines remain one of the most important pillars in preventative medicine, providing protection
against a wide array of diseases by inducing humoral and/or cellular immunity. Of the …