Mycobacterium tuberculosis (Mtb) survives under oxidatively hostile environments encountered
inside host phagocytes. To protect itself from oxidative stress, Mtb produces millimolar …

Global gene expression profiling has emerged as a major tool in understanding complex
response patterns of biological systems to perturbations. However, a lack of unbiased …

The pursuit to improve the TB control program comprising one approved vaccine, M. bovis
Bacille Calmette-Guerin (BCG) has directed researchers to explore progressive approaches …

Glutathione (GSH) is an abundant natural tripeptide with antioxidant properties. Under different
conditions, it can play protective as well as pathogenic roles. The redox state of the cell …

Human telomerase reverse transcriptase is an essential rate-limiting component of telomerase
complex. hTERT protein in association with other proteins and the human telomerase …

Protein kinase G (PknG), a thioredoxin-fold–containing eukaryotic-like serine/threonine
protein kinase, is a virulence factor in Mycobacterium tuberculosis, required for inhibition of …

Stimulation of naïve T cells during primary infection or vaccination drives the differentiation
and expansion of effector and memory T cells that mediate immediate and long-term …

Mycobacterium tuberculosis (Mtb) has evolved protective and detoxification mechanisms to
maintain cytoplasmic redox balance in response to exogenous oxidative stress encountered …

The currently available anti-tuberculosis treatment (ATT) comprises exclusively of anti-bacterial
drugs, is very lengthy, has adverse side effects on the host and leads to the generation of …

Mycobacterium tuberculosis (Mtb) employs plethora of mechanisms to hijack the host defence
machinery for its successful survival, proliferation and persistence. Here, we show that Mtb …