Measles virus is directly responsible for more than 100,000 deaths yearly. Epidemiological
studies have associated measles with increased morbidity and mortality for years after …

Measles is an acute viral disease associated both with immune suppression and development
of life-long immunity. Clearance of measles virus (MeV) involves rapid elimination of …

Congenital and perinatal infections are transmitted from mother to infant during pregnancy
across the placenta or during delivery. These infections not only cause pregnancy …

Recovery from measles results in life-long protective immunity. To understand induction of
long-term immunity, rhesus macaques were studied for 6 months after infection with wild-type …

Measles is an acute systemic viral disease with initial amplification of infection in lymphoid
tissue and subsequent spread over 10–14 days to multiple organs. Failure of the innate …

To identify immune factors present during the acute rash phase of measles and associations
with outcome and human immunodeficiency virus type 1 (HIV-1) coinfection, we measured …

Early initiation of antiretroviral therapy (ART) significantly improves clinical outcomes and
reduces mortality of infants/children living with HIV. However, the ability of infected cells to …

Purpose of Review In the absence of antiretroviral therapy (ART), more than 50% of perinatally
HIV-infected children die by 2 years of age. Early ART from infancy is therefore a global …

Global elimination of pediatric human immunodeficiency virus (HIV) infections will require
the development of novel immune-based approaches, and understanding infant immunity to …

Widespread availability of antiretroviral therapy among pregnant women living with HIV has
greatly reduced the rate of mother-to-child transmission (MTCT) of HIV across the globe. …