Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both
genetic and environmental factors. The exact nature of the environmental factors responsible …

Two zoonotic coronaviruses (CoVs)—SARS-CoV and MERS-CoV—have crossed species
to cause severe human respiratory disease. Here, we showed that induction of airway …

The human gut contains trillions of bacteria (microbiome) that play a major role in maintaining
a healthy state for the host. Perturbation of this healthy gut microbiome might be an …

Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system
with unknown etiology. Recently, the gut microbiota has emerged as a potential factor in …

Antigenic stimulation promotes T cell metabolic reprogramming to meet increased biosynthetic,
bioenergetic, and signaling demands. We show that the one-carbon (1C) metabolism …

The MHC in humans encodes the most polymorphic genes, the HLA genes, which are critical
for the immune system to clear infection. This can be attributed to strong selection pressure …

The gut microbiota is a potential environmental factor that influences the development of
multiple sclerosis (MS). We and others have demonstrated that patients with MS and healthy …

WASH is an Arp2/3 activator of the Wiskott-Aldrich syndrome protein superfamily that functions
during endosomal trafficking processes in collaboration with the retromer and sorting …

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. We and
others have shown that there is enrichment or depletion of some gut bacteria in MS patients …

We performed untargeted metabolomics in plasma of B6 mice with experimental autoimmune
encephalitis (EAE) at the chronic phase of the disease in search of an altered metabolic …