User profiles for Assaf Katz

Assaf Katz Zondek

Universidad de Chile
Verified email at u.uchile.cl
Cited by 762

Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center

…, P Küpfer, D Evéquoz, G Fernandez, A Katz… - Nucleic acids …, 2018 - academic.oup.com
Intracellular levels of reactive oxygen species (ROS) increase as a consequence of oxidative
stress and represent a major source of damage to biomolecules. Due to its high cellular …

[HTML][HTML] EF-P dependent pauses integrate proximal and distal signals during translation

S Elgamal, A Katz, SJ Hersch, D Newsom, P White… - PLoS …, 2014 - journals.plos.org
Elongation factor P (EF-P) is required for the efficient synthesis of proteins with stretches of
consecutive prolines and other motifs that would otherwise lead to ribosome pausing. …

Non‐canonical roles of tRNAs and tRNA mimics in bacterial cell biology

A Katz, S Elgamal, A Rajkovic, M Ibba - Molecular microbiology, 2016 - Wiley Online Library
Transfer RNAs (tRNAs) are the macromolecules that transfer activated amino acids from
aminoacyl‐tRNA synthetases to the ribosome, where they are used for the mRNA guided …

[HTML][HTML] Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile

V Bravo, A Katz, L Porte, T Weitzel… - PLoS Neglected …, 2021 - journals.plos.org
Campylobacter jejuni and Campylobacter coli are the leading cause of human gastroenteritis
in the industrialized world and an emerging threat in developing countries. The incidence …

[HTML][HTML] Translation initiation rate determines the impact of ribosome stalling on bacterial protein synthesis

SJ Hersch, S Elgamal, A Katz, M Ibba… - Journal of Biological …, 2014 - ASBMB
Ribosome stalling during translation can be caused by a number of characterized mechanisms.
However, the impact of elongation stalls on protein levels is variable, and the reasons for …

[HTML][HTML] Regulation of leaderless mRNA translation in bacteria

LE Leiva, A Katz - Microorganisms, 2022 - mdpi.com
In bacteria, the translation of genetic information can begin through at least three different
mechanisms: canonical or Shine-Dalgarno-led initiation, readthrough or 70S scanning …

Regulation of a glutamyl-tRNA synthetase by the heme status

G Levicán, A Katz, M De Armas… - Proceedings of the …, 2007 - National Acad Sciences
Glutamyl-tRNA (Glu-tRNA), formed by Glu-tRNA synthetase (GluRS), is a substrate for
protein biosynthesis and tetrapyrrole formation by the C 5 pathway. In this route Glu-tRNA is …

[HTML][HTML] Modulation of Escherichia coli Translation by the Specific Inactivation of tRNAGly Under Oxidative Stress

…, D Gutiérrez, SA Leidel, M Ibba, A Katz - Frontiers in …, 2020 - frontiersin.org
Bacterial oxidative stress responses are generally controlled by transcription factors that
modulate the synthesis of RNAs with the aid of some sRNAs that control the stability, and in …

[HTML][HTML] Whole-genome sequencing reveals changes in genomic diversity and distinctive repertoires of T3SS and T6SS effector candidates in Chilean clinical …

A Katz, L Porte, T Weitzel, C Varela… - Frontiers in cellular …, 2023 - ncbi.nlm.nih.gov
Campylobacter is the leading cause of bacterial gastroenteritis worldwide and an emerging
and neglected pathogen in South America. This zoonotic pathogen colonizes the …

ICEAfe1, an actively excising genetic element from the biomining bacterium Acidithiobacillus ferrooxidans

…, PC Covarrubias, G Levicán, A Katz… - Journal of Molecular …, 2013 - karger.com
Integrative conjugative elements (ICEs) are self-transferred mobile genetic elements that
contribute to horizontal gene transfer. An ICE (ICEAfe1) was identified in the genome of …