Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

Context A variety of topical and systemic drugs are available to treat primary Sjögren syndrome,
although no evidence-based therapeutic guidelines are currently available. Objective To …

The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in
recent decades: treatment decisions remain challenging in clinical practice, without a specific …

Sicca features are the central clinical manifestations of Sjögren’s syndrome (SS), but recent
studies have confirmed that primary SS has a systemic expression, including extraglandular …

Human mononuclear phagocytes comprise phenotypically and functionally overlapping
subsets of dendritic cells (DCs) and monocytes, but the extent of their heterogeneity and distinct …

Objective. To prospectively investigate whether mixed monoclonal cryoglobulinemia (MMC)
and monoclonal rheumatoid factor (mRF)-associated crossreactive idiotypes (CRI) serve as …

Haematological abnormalities are common in systemic lupus erythematosus. Anaemia is
found in about 50% of patients, with anaemia of chronic disease being the most common form. …

Sjögren's syndrome (SS), a chronic autoimmune disorder, particularly compromises the
function of exocrine glands. The involvement of these glands is characterized by focal, …

Objective: To evaluate the safety and effectiveness of adalimumab alone or in combination
with standard disease-modifying antirheumatic drugs (DMARDs) for the treatment of …

Aerosols with lacrimatory, sternutatory, and general irritant properties (harassing agents, riot
control agents, or “tear gas") are used worldwide by civilian police and military authorities to …