[HTML][HTML] A cAMP-related gene network in microglia is inversely regulated by morphine tolerance and withdrawal
Background Microglia have recently been implicated in opioid dependence and withdrawal.
Mu opioid receptors are expressed in microglia, and microglia form intimate connections …
Mu opioid receptors are expressed in microglia, and microglia form intimate connections …
Sequencing the serotonergic neuron translatome reveals a new role for Fkbp5 in stress
Serotonin is a key mediator of stress, anxiety, and depression, and novel therapeutic targets
within serotonin neurons are needed to combat these disorders. To determine how stress …
within serotonin neurons are needed to combat these disorders. To determine how stress …
Restoration of physiological expression of 5-HT6 receptor into the primary cilia of null mutant neurons lengthens both primary cilia and dendrites
AJ Lesiak, M Brodsky, N Cohenca, AG Croicu… - Molecular …, 2018 - ASPET
5-HT 6 (serotonin) receptors are promising targets for a variety of neuropsychiatric disorders
and have been linked to several cellular signaling cascades. Endogenous 5-HT 6 receptors …
and have been linked to several cellular signaling cascades. Endogenous 5-HT 6 receptors …
[HTML][HTML] Stress induces divergent gene expression among lateral habenula efferent pathways
Running Title: LHb efferent pathways diverge after stressAbstract word count:
192Introduction word count including citations: 719Discussion word count including citations: …
192Introduction word count including citations: 719Discussion word count including citations: …
5-HT1B Receptor-Mediated Activation of ERK1/2 Requires Both Gαi/o and β-Arrestin Proteins
…, AW Gibson, MR Levinstein, AJ Lesiak… - ACS chemical …, 2019 - ACS Publications
5-HT 1B receptors modulate synaptic serotonin (5-HT) levels and play a significant role in
the regulation of emotional behaviors. These receptors are Gα i/o -coupled and inhibit …
the regulation of emotional behaviors. These receptors are Gα i/o -coupled and inhibit …
[HTML][HTML] Turning towards greater equity and access with online teacher professional development
AJ Lesiak, JC Griswold, H Starks - Journal of STEM outreach, 2021 - ncbi.nlm.nih.gov
Access to professional development opportunities promotes equity for both teachers and
students. We identified time, distance, and childcare needs as limiting factors for teachers …
students. We identified time, distance, and childcare needs as limiting factors for teachers …
Ribotag-seq reveals a compensatory camp responsive gene network in striatal microglia induced by morphine withdrawal
Microglia have recently been implicated in dependence to opioids. To investigate this
directly, we used RNA sequencing of ribosome associated RNAs from striatal microglia (RiboTag-…
directly, we used RNA sequencing of ribosome associated RNAs from striatal microglia (RiboTag-…
[PDF][PDF] A Creative Communication Partnership to Promote Curricula Dissemination on Social Media
AJ Lesiak, N Malik, JC Griswold - Journal of STEM Outreach, 2024 - jstemoutreach.org
Genome Sciences Education Outreach (GSEO) has developed innovative programs that
bring leading-edge science to teachers and students in K-12 schools. Disseminating …
bring leading-edge science to teachers and students in K-12 schools. Disseminating …
RiboTag-Seq Reveals the Activation of the Unfolded Protein Response in Striatal Microglia Induced by Ethanol Withdrawal
Repeated cycles of alcohol intoxication and withdrawal both induce profound changes in
gene expression that can contribute to the physiological and behavioral consequences of …
gene expression that can contribute to the physiological and behavioral consequences of …
Blood Sugar Balance: A Glucose Metabolism Web Game for Diabetes Education
AJ Lesiak, JC Griswold - The American biology teacher, 2023 - online.ucpress.edu
Blood Sugar Balance (BSB) is an accessible web-based game, created as an extension of
our federally funded type 2 diabetes curriculum for high school biology classrooms. Modeling …
our federally funded type 2 diabetes curriculum for high school biology classrooms. Modeling …