During the past decades, several methods (eg, electron microscopy, flow chamber experiments,
surface chemical analysis, surface charge and surface hydrophobicity measurements) …

Knowledge of the mechanisms by which bacterial pili adhere to host cells and withstand
external forces is critical to our understanding of their functional roles and offers exciting …

Single-cell force spectroscopy is a powerful atomic force microscopy modality in which a
single living cell is attached to the atomic force microscopy cantilever to quantify the forces that …

A variety of bacterial pathogens use nanoscale protein fibers called type IV pili to mediate
cell adhesion, a primary step leading to infection. Currently, how these nanofibers respond to …

In Aspergillus fumigatus , the conidial surface contains dihydroxynaphthalene (DHN)-melanin.
Six-clustered gene products have been identified that mediate sequential catalysis of DHN…

SdrG is a cell surface adhesin from S taphylococcus epidermidis which binds to the blood
plasma protein fibrinogen ( Fg ). Ligand binding follows a ‘dock, lock and latch’ model …

The development of bacterial biofilms on surfaces leads to hospital-acquired infections that
are difficult to fight. In Staphylococci, the cationic polysaccharide intercellular adhesin (PIA) …

Cellular morphogenesis in the fungal pathogen Candida albicans is associated with
changes in cell wall composition that play important roles in biofilm formation and immune …

Despite the clinical importance of bacterial–fungal interactions, their molecular details are
poorly understood. A hallmark of such medically important interspecies associations is the …

Although bacterial pili are known to mediate cell adhesion to a variety of substrates, the
molecular interactions behind this process are poorly understood. We report the direct …