Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant,
pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained …

DDX41 germline mutations (DDX41 MutGL ) are the most common genetic predisposition to
myelodysplastic syndrome and acute myeloid leukemia (AML). Recent reports suggest that …

The outcome of acute myeloid leukemia patients aged 70 years or older is poor. Defining the
best treatment option remains controversial especially when choosing between intensive …

FIP1L1‐PDGFRA‐positive myeloid neoplasm with eosinophilia (F/P+ MN‐eo) is a rare disease:
robust epidemiological data are lacking and reported issues are scarce, of low sample‐…

Internal tandem duplication in Fms-like tyrosine kinase 3 (FLT3-ITD) is the most frequent
mutation observed in acute myeloid leukemia (AML) and correlates with poor prognosis. FLT3 …

Multiple cytogenetic subgroups have been described in adult Philadelphia chromosome (Ph)-negative
B-cell precursor (BCP) acute lymphoblastic leukemia (ALL), often comprising …

For nearly 3 decades, the human MLL (KMT2A) gene and its rearrangements have been
investigated in many different laboratories around the world. At our diagnostic center (DCAL …

NPM 1-mutated acute myeloid leukemia (AML) shows unique features. However, the
characteristics of “therapy-related” NPM1-mutated AML (t-NPM1 AML) are poorly understood. We …

Classifications of acute myeloid leukemia (AML) patients rely on morphologic, cytogenetic,
and molecular features. Here we have established a novel flow cytometry-based …

Simple Summary In acute myeloid leukemia (AML), minimal/measurable residual disease (MRD)
can be assessed based on molecular markers or immunophenotypic features …