User profiles for Audrey Le Gouellec
Audrey LE GOUELLECUniversité Grenoble Alpes & CHU Grenoble Alpes Verified email at chu-grenoble.fr Cited by 2090 |
Live-attenuated bacteria as a cancer vaccine vector
…, Y Wang, B Polack, AL Gouëllec - Expert review of …, 2013 - Taylor & Francis
In the emerging field of active and specific cancer immunotherapy, strategies using live-attenuated
bacterial vectors have matured in terms of academic and industrial development. …
bacterial vectors have matured in terms of academic and industrial development. …
Feature-based molecular networking in the GNPS analysis environment
Molecular networking has become a key method to visualize and annotate the chemical space
in non-targeted mass spectrometry data. We present feature-based molecular networking …
in non-targeted mass spectrometry data. We present feature-based molecular networking …
[HTML][HTML] What Is New in the Anti–Pseudomonas aeruginosa Clinical Development Pipeline Since the 2017 WHO Alert?
S Reig, A Le Gouellec, S Bleves - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and mortality
worldwide. Carbapenem-resistant Pseudomonas aeruginosa (CRPA) are considered “…
worldwide. Carbapenem-resistant Pseudomonas aeruginosa (CRPA) are considered “…
Scavenging of reactive oxygen species by tryptophan metabolites helps Pseudomonas aeruginosa escape neutrophil killing
C Genestet, A Le Gouellec, H Chaker, B Polack… - Free Radical Biology …, 2014 - Elsevier
Pseudomonas aeruginosa is responsible for persistent infections in cystic fibrosis patients,
suggesting an ability to circumvent innate immune defenses. This bacterium uses the …
suggesting an ability to circumvent innate immune defenses. This bacterium uses the …
[HTML][HTML] Ion identity molecular networking for mass spectrometry-based metabolomics in the GNPS environment
Molecular networking connects mass spectra of molecules based on the similarity of their
fragmentation patterns. However, during ionization, molecules commonly form multiple ion …
fragmentation patterns. However, during ionization, molecules commonly form multiple ion …
ReDU: a framework to find and reanalyze public mass spectrometry data
…, SA Jarmusch, KL Jones, Z Kamenik, A Le Gouellec… - Nature …, 2020 - nature.com
We present ReDU ( https://redu.ucsd.edu/ ), a system for metadata capture of public mass
spectrometry-based metabolomics data, with validated controlled vocabularies. Systematic …
spectrometry-based metabolomics data, with validated controlled vocabularies. Systematic …
[HTML][HTML] Complement alternative and mannose-binding lectin pathway activation is associated with COVID-19 mortality
…, T Raskovalova, M Pernollet, A Le Gouellec… - Frontiers in …, 2021 - frontiersin.org
Background The SARS-CoV-2 infection triggers excessive immune response resulting in
increased levels of pro-inflammatory cytokines, endothelial injury, and intravascular …
increased levels of pro-inflammatory cytokines, endothelial injury, and intravascular …
[HTML][HTML] Tryptophan catabolism in Pseudomonas aeruginosa and potential for inter-kingdom relationship
…, K Faure, E Kipnis, B Toussaint, A Le Gouellec - BMC microbiology, 2016 - Springer
Background Pseudomonas aeruginosa (Pa) is a Gram-negative bacteria frequently involved
in healthcare-associated pneumonia with poor clinical outcome. To face the announced …
in healthcare-associated pneumonia with poor clinical outcome. To face the announced …
[HTML][HTML] A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to β-lactam antibiotics
L Pernot, L Chesnel, A Le Gouellec, J Croizé… - Journal of Biological …, 2004 - ASBMB
The human pathogen Streptococcus pneumoniae is one of the main causative agents of
respiratory tract infections. At present, clinical isolates of S. pneumoniae often exhibit decreased …
respiratory tract infections. At present, clinical isolates of S. pneumoniae often exhibit decreased …
[HTML][HTML] Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
C Morlot, L Pernot, A Le Gouellec, AM Di Guilmi… - Journal of Biological …, 2005 - ASBMB
Penicillin-binding proteins (PBPs) are membrane-associated enzymes which perform
critical functions in the bacterial cell division process. The single d-Ala,d-Ala (d,d)-…
critical functions in the bacterial cell division process. The single d-Ala,d-Ala (d,d)-…