Over 6,000 fragments from the genome of Drosophila melanogaster were analyzed for their
ability to drive expression of GAL4 reporter genes in the third-instar larval imaginal discs. …

Skeletal muscle serves as a paradigm for the acquisition of cell fate, yet the relationship
between primitive cell populations and emerging myoblasts has remained elusive. We identify a …

Skeletal muscle stem cell fate in adult mice is regulated by crucial transcription factors,
including the determination genes Myf5 and Myod. The precise role of Myf5 in regulating …

The appendages of arthropods and vertebrates are not homologous structures, although the
underlying genetic mechanisms that pattern them are highly conserved. Members of the Sp …

Multiple cell types arise from cells in the dermomyotome of the somite that express Pax3
and Pax7, and myogenesis is regulated by Notch signaling. The asymmetric cell fate …

With the rapid emergence of variants of concern (VOC), the efficacy of currently licensed
vaccines has reduced drastically. VOC mutations largely occur in the S1 subunit of Spike. The …

We characterized the establishment of an Epidermal Growth Factor Receptor (EGFR)
organizing center (EOC) during leg development in Drosophila melanogaster. Initial EGFR …

Our recent findings demonstrated that the histone chaperone and DNA repair factor
aprataxin and PNK-like factor (APLF) could regulate epithelial to mesenchymal transition (EMT) …

Après la récente identification des cellules souches du muscle squelettique, on commence
à étudier les mécanismes de régulation génique impliqués dans leur autorenouvellement et …

theses.fr – Aurélie Jory , Caractérisation moléculaire et cellulaire des progéniteurs du muscle
squelettique chez la souris : numb et son influence sur la régionalisation du somite et ses …