Using a discrete, intracellular 19 F nuclear magnetic resonance (NMR) probe on transmembrane
helix 6 of the neurotensin receptor 1 (NTS1), we aim to understand how ligands and …

Malonyl-thioesters are reactive centers of malonyl-CoA and malonyl-S-acyl carrier protein,
essential to fatty acid, polyketide and various specialized metabolite biosynthesis. Enzymes …

Fluorine ( 19 F) offers several distinct advantages for biomolecular nuclear magnetic resonance
spectroscopy such as no background signal, 100% natural abundance, high sensitivity, …

Using a discrete, intracellular 19 F-NMR probe on transmembrane helix 6 (TM6) of the
Neurotensin receptor 1 (NTS1), we aim to understand how ligands and transducers modulate the …

Background Intact sensorimotor function of the upper extremity is essential for successfully
performing activities of daily living. After a stroke, upper limb function is often compromised …

For nearly a century, biologists have emphasized the profound importance of spatial scale
for ecology, evolution and conservation. Nonetheless, objectively identifying critical scales …

G protein-coupled receptors (GPCRs) are the largest integral membrane protein class in
eukaryotes with over 800 unique members that regulate numerous biological processes …

Background ST ‐segment–elevation myocardial infarction is associated with an intense acute
inflammatory response and risk of heart failure. We tested whether interleukin‐1 blockade …

This paper investigates economic and political factors in suburban annexation decision in
large US cities. This paper employs a median-voter model, which suggests a natural latent-…

Objective In North America, tuberculosis and nontuberculous mycobacterial (NTM) disease
rates associated with antitumour necrosis factor α (anti-TNFα) therapy are unknown. Methods …