We investigated type 2 diabetes (T2D) genetic susceptibility via multi-ancestry meta-analysis
of 228,499 cases and 1,178,783 controls in the Million Veteran Program (MVP), DIAMANTE…

We report a genome-wide association study (GWAS) of coronary artery disease (CAD)
incorporating nearly a quarter of a million cases, in which existing studies are integrated with data …

INTRODUCTION The human genome contains tens of thousands of rare (minor allele frequency
<1%) variants, some of which contribute to disease risk. Using 838 samples with whole-…

Similarities between speech and birdsong make songbirds advantageous for investigating
the neurogenetics of learned vocal communication—a complex phenotype probably …

Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future
symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may …

In most species, females time reproduction to coincide with fertility. Thus, identifying factors
that signal fertility to the brain can provide access to neural circuits that control sexual …

A major challenge of genome-wide association studies (GWASs) is to translate phenotypic
associations into biological insights. Here, we integrate a large GWAS on blood lipids …

Background Genetic variants within nearly 1000 loci are known to contribute to modulation
of blood lipid levels. However, the biological pathways underlying these associations are …

Polygenic risk scores (PRSs) are central to the development of precision medicine. However,
decades of Euro-centric genomics research have paved the way for disparities in their …

SARS-CoV-2 has caused symptomatic COVID-19 and widespread death across the globe.
We sought to determine genetic variants contributing to COVID-19 susceptibility and …