User profiles for Avishek Singh

Avishek Kumar Singh

Assistant Professor, Mayo Clinic, Rochester
Verified email at mayo.edu
Cited by 387

[PDF][PDF] Global microRNA expression profiling in the liver biopsies of hepatitis B virus–infected patients suggests specific microRNA signatures for viral persistence and …

AK Singh, SB Rooge, A Varshney, M Vasudevan… - …, 2018 - Wiley Online Library
Hepatitis B virus (HBV) can manipulate the microRNA (miRNA) regulatory networks in infected
cells to create a permissive environment for viral replication, cellular injury, disease onset, …

Targeted delivery of microRNA‐199a‐3p using self‐assembled dipeptide nanoparticles efficiently reduces hepatocellular carcinoma in mice

A Varshney, JJ Panda, AK Singh, N Yadav… - …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is an aggressive tumor with limited systemic and locoregional
modalities of treatment. Although microRNA (miRNA) based therapies have significant …

Differences in transforming growth factor‐β1/BMP7 signaling and venous fibrosis contribute to female sex differences in arteriovenous fistulas

C Cai, S Kilari, AK Singh, C Zhao… - Journal of the …, 2020 - Am Heart Assoc
Background Women have decreased hemodialysis arteriovenous fistula (AVF) maturation
and patency rates. We determined the mechanisms responsible for the sex‐specific …

Periadventitial Delivery of Simvastatin‐Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula

…, ST Zuckerman, C Cai, S Kilari, A Singh… - Journal of the …, 2020 - Am Heart Assoc
Background Venous neointimal hyperplasia and venous stenosis (VS) formation can result in
a decrease in arteriovenous fistula (AVF) patency in patients with end‐stage renal disease. …

1α, 25-dihydroxyvitamin D3 encapsulated in nanoparticles prevents venous neointimal hyperplasia and stenosis in porcine arteriovenous fistulas

AK Singh, C Cai, S Kilari, C Zhao… - Journal of the …, 2021 - journals.lww.com
Background Few therapies prevent venous neointimal hyperplasia (VNH) and venous
stenosis (VS) formation in arteriovenous fistulas (AVF). Expression of the immediate early …

[PDF][PDF] Extracellular vesicles from hepatitis B patients serve as reservoir of hepatitis B virus DNA

…, JS Maras, S Sharma, S Thangariyal, A Singh… - J Viral Hepat, 2019 - academia.edu
Hepatitis B virus (HBV) is responsible for half of the deaths globally from viral hepatitis. The
interplay between viral replication and host immune response determines the natural course …

[HTML][HTML] Adventitial delivery of nanoparticles encapsulated with 1α, 25-dihydroxyvitamin D3 attenuates restenosis in a murine angioplasty model

C Cai, S Kilari, C Zhao, AK Singh, ML Simeon… - Scientific reports, 2021 - nature.com
Percutaneous transluminal angioplasty (PTA) of stenotic arteriovenous fistulas (AVFs) is
performed to maintain optimal function and patency. The one-year patency rate is 60% because …

Bindarit encapsulated nanoparticles prevent venous neointimal hyperplasia and restenosis in a murine angioplasty model

AK Singh, S Kilari, C Cai, S Misra - Translational Research, 2022 - Elsevier
… Author links open overlay panel AVISHEK K. Singh 1 , SREENIVASULU KILARI 1 , … AK
Singh performed a significant portion of experiments. S. Kilari contributed to Rheologic, …

[HTML][HTML] Neuropilin-1 deficiency in vascular smooth muscle cells is associated with hereditary hemorrhagic telangiectasia arteriovenous malformations

S Kilari, Y Wang, A Singh, RP Graham, V Iyer… - JCI insight, 2022 - ncbi.nlm.nih.gov
Patients with hereditary hemorrhagic telangiectasia (HHT) have arteriovenous malformations
(AVMs) with genetic mutations involving the activin-A receptor like type 1 (ACVRL1 or ALK1…

Key elements of the RNAi pathway are regulated by hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing

M Chinnappan, AK Singh, PK Kakumani… - Biochemical …, 2014 - portlandpress.com
The host-mediated RNAi pathways restrict replication of viruses in plant, invertebrate and
vertebrate systems. However, comparatively little is known about the interplay between RNAi …