User profiles for Avraam Tapinos

Avraam Tapinos

The University of Manchester
Verified email at manchester.ac.uk
Cited by 223

[HTML][HTML] Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

…, A Sanni, M Ajani, JB Reynier, A Tapinos… - Nature …, 2021 - nature.com
Black women across the African diaspora experience more aggressive breast cancer with
higher mortality rates than white women of European ancestry. Although inter-ethnic germline …

Challenges in the analysis of viral metagenomes

R Rose, B Constantinides, A Tapinos… - Virus …, 2016 - academic.oup.com
Genome sequencing technologies continue to develop with remarkable pace, yet analytical
approaches for reconstructing and classifying viral genomes from mixed samples remain …

[HTML][HTML] A signal processing method for alignment-free metagenomic binning: multi-resolution genomic binary patterns

S Kouchaki, A Tapinos, DL Robertson - Scientific reports, 2019 - nature.com
Algorithms in bioinformatics use textual representations of genetic information, sequences
of the characters A, T, G and C represented computationally as strings or sub-strings. Signal …

Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients.

A Everall, A Tapinos, A Hawari, A Cornish, A Sud… - medRxiv, 2023 - medrxiv.org
Whole genome sequencing (WGS) allows exploration of the complete compendium of
oncogenic processes generating characteristic patterns of mutations. Mutational signatures …

[HTML][HTML] Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma

…, C Bachert, S Finotto, T Jartti, A Tapinos… - Scientific Reports, 2023 - nature.com
Asthma development and exacerbation is linked to respiratory virus infections. There is limited
information regarding the presence of viruses during non-exacerbation/infection periods. …

[HTML][HTML] A method for comparing multivariate time series with different dimensions

A Tapinos, P Mendes - PloS one, 2013 - journals.plos.org
In many situations it is desirable to compare dynamical systems based on their behavior.
Similarity of behavior often implies similarity of internal mechanisms or dependency on …

[HTML][HTML] The utility of data transformation for alignment, De Novo assembly and classification of short read virus sequences

A Tapinos, B Constantinides, MVT Phan, S Kouchaki… - Viruses, 2019 - mdpi.com
Advances in DNA sequencing technology are facilitating genomic analyses of unprecedented
scope and scale, widening the gap between our abilities to generate and fully exploit …

Bacteriophage deficiency characterizes respiratory virome dysbiosis in childhood asthma

…, T Jartti, ML Kowalski, AG Sotiropoulos, A Tapinos… - BioRxiv, 2020 - biorxiv.org
Asthma development and persistence is tightly linked to respiratory viruses. Viral presence
is usually interrogated with targeted approaches during periods of disease activity and/or …

[HTML][HTML] Investigation of Salmonella phage–bacteria infection profiles: network structure reveals a gradient of target-range from generalist to specialist phage clones in …

…, N Grdzelishvili, B Stamp, E Herman, A Tapinos… - Viruses, 2021 - mdpi.com
Bacteriophages that lyse Salmonella enterica are potential tools to target and control
Salmonella infections. Investigating the host range of Salmonella phages is a key to understand …

Local binary patterns as a feature descriptor in alignment-free visualisation of metagenomic data

S Kouchaki, S Tirunagari, A Tapinos… - … Symposium Series on …, 2016 - ieeexplore.ieee.org
Shotgun sequencing has facilitated the analysis of complex microbial communities. However,
clustering and visualising these communities without prior taxonomic information is a …