Three-dimensional (3D) organoids can serve as an in vitro platform to study cell–cell interactions,
tissue development, and toxicology. Development of organoids with tissue architecture …

In mammalian testis, contractile peritubular myoid cells (PMCs) regulate the transport of
sperm and luminal fluid, while secreting growth factors and extracellular matrix proteins to …

In many tissues, homeostasis is maintained by physical contact between stem cells and an
anatomically defined niche. However, how stem cell homeostasis is achieved in …

Dermal fibroblasts exhibit considerable heterogeneity during homeostasis and in response
to injury. Defining lineage origins of reparative fibroblasts and regulatory programs that drive …

USP9X (ubiquitin-specific peptidase 9, X chromosome) is the mammalian orthologue of
Drosophila deubiquitinase fat facets that was previously shown to regulate the maintenance of …

In mouse testes, spermatogonial stem cells (SSCs), a subpopulation of GFRα1 (GDNF
family receptor-α1)-positive spermatogonia, are widely distributed along the convoluted …

Introduction Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) are risk
factors for early onset of Alzheimer's disease (AD) and may accelerate the progression rate of …

Seminiferous tubules (STs) in the mammalian testes are connected to the rete testis (RT) via
a Sertoli valve (SV). Spermatozoa produced in the STs are released into the tubular luminal …

In most mammals, the sex of the gonads is based on the fate of the supporting cell lineages,
which arises from the proliferation of coelomic epithelium (CE) that surfaces on the …

In mammalian testes, undifferentiated spermatogonia (A undiff ) undergo differentiation in
response to retinoic acid (RA), while their progenitor states are partially maintained by …