Deleterious alleles constantly enter populations through mutation. Understanding the nature
of selection against such alleles is required to assess their impact on populations. In a …

Drosophila melanogaster photoreceptor cells are highly polarized epithelial cells. Their
apical membrane is further subdivided into the stalk membrane and the light-sensing …

Vesicle trafficking is an essential process required for a multitude of cell behaviors, including
cell signaling and membrane polarization. Problems in vesicle trafficking have been linked …

… I would like to thank all of the Agrawal lab in the past two years especially Azadeh
Laffafian, James King, Sean Clarke, for everything from advice to sharing laughs. …

Population structure can dramatically alter mutation load, but the magnitude and direction of
this effect depend on whether selection is soft or hard. The abstract nature of previous load …

Understanding the nature of selection against deleterious alleles is central to determining
how populations are affected by the constant influx of new mutations. Important progress has …

… Laffafian комментирует ситуацию следующим образом: "В целом, ожидается, что …
Azadeh Laffafian, PhD, medical devices analyst at GlobalData, comments: "Overall, the COVID-19 …