User profiles for Azger Dusthackeer

Azger Dusthackeer

National Institute for Research in Tuberculosis
Verified email at nirt.res.in
Cited by 841

[HTML][HTML] Drug resistance among extrapulmonary TB patients: Six years experience from a supranational reference laboratory

A Dusthackeer, G Sekar, S Chidambaram… - Indian Journal of …, 2015 - journals.lww.com
Methods: Extrapulmonary specimens received from referring hospitals were decontaminated
and cultured using standard procedures. Drug susceptibility testing (DST) for …

[HTML][HTML] Differential Culturability of Mycobacterium tuberculosis in Culture-Negative Sputum of Patients With Pulmonary Tuberculosis and in a Simulated Model of …

A Dusthackeer, M Balasubramanian… - Frontiers in …, 2019 - frontiersin.org
Tuberculosis (TB) remains a leading killer among infectious diseases of humans worldwide.
Delayed diagnosis is a crucial problem in global TB control programs. Bacteriological …

[HTML][HTML] Extrapulmonary tuberculosis—an update on the diagnosis, treatment and drug resistance

R Gopalaswamy, VNA Dusthackeer, S Kannayan… - Journal of …, 2021 - mdpi.com
Pathogenic Mycobacterium tuberculosis complex organisms (MTBC) primarily cause
pulmonary tuberculosis (PTB); however, MTBC are also capable of causing disease in …

Factors influencing tuberculosis treatment outcome in adult patients treated with thrice-weekly regimens in India

…, V Rajagandhi, A Dusthackeer… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The Indian Revised National Tuberculosis (TB) Control Programme uses thrice-weekly
treatment with standard drug dosages. The role of plasma drug levels and other factors in …

A multi-targeting pre-clinical candidate against drug-resistant tuberculosis

…, CR Nirmal, B Mahizhaveni, A Dusthackeer… - Tuberculosis, 2021 - Elsevier
FNDR-20081 [4-{4-[5-(4-Isopropyl-phenyl)- [1,2,4]oxadiazol-3-ylmethyl]-piperazin-1-yl}-7-pyridin-3-yl-quinoline]
is a novel, first in class anti-tubercular pre-clinical candidate against …

Formulation and evaluation of β-cyclodextrin-mediated inclusion complexes of isoniazid scaffolds: molecular docking and in vitro assessment of antitubercular …

L Tom, CR Nirmal, A Dusthackeer… - New Journal of …, 2020 - pubs.rsc.org
Poor aqueous solubility is the major problem encountered with formulation of new bioactive
chemical entities. In the present study, we report the synthesis and evaluation of inclusion …

Construction and evaluation of luciferase reporter phages for the detection of active and non-replicating tubercle bacilli

A Dusthackeer, V Kumar, S Subbian… - Journal of …, 2008 - Elsevier
The luciferase reporter phages (LRP) show great promise for diagnostic mycobacteriology.
Though conventional constructs developed from lytic phages such as D29 and TM4 are …

Chrysomycin A inhibits the topoisomerase I of Mycobacterium tuberculosis

B Muralikrishnan, LK Edison, A Dusthackeer… - The Journal of …, 2022 - nature.com
Novel anti-tuberculosis drugs are essential to manage drug-resistant tuberculosis, caused
by Mycobacterium tuberculosis. We recently reported the antimycobacterial activity of …

Anti-tubercular and probiotic properties of coagulase-negative staphylococci isolated from Koozh, a traditional fermented food of South India

A Khusro, C Aarti, A Dusthackeer, P Agastian - Microbial pathogenesis, 2018 - Elsevier
In the last few years, the demand for the tremendous therapeutic applications of indigenous
probiotic bacteria from diversified fermented food products has surged. In view of this, the …

Antimycobacterial potentials of quercetin and rutin against Mycobacterium tuberculosis H37Rv

K Sasikumar, AR Ghosh, A Dusthackeer - 3 Biotech, 2018 - Springer
Quercetin and rutin, two flavonoids were examined for antimycobacterial activities against M.
tuberculosis H37Rv (ATCC 27294). The quercetin exhibited (99.30 ± 0.268%) in (LRP) …