User profiles for Azzam Ismail

Ts. Dr. Muhammad Azzam Ismail

Senior Lecturer at University of Malaya
Verified email at um.edu.my
Cited by 957

[PDF][PDF] Glioma progression is shaped by genetic evolution and microenvironment interactions

…, D Brat, PV Gould, A Wöehrer, K Aldape, A Ismail… - Cell, 2022 - cell.com
The factors driving therapy resistance in diffuse glioma remain poorly understood. To
identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …

Longitudinal molecular trajectories of diffuse glioma in adults

…, PV Gould, MR Grimmer, A Iavarone, A Ismail… - Nature, 2019 - nature.com
The evolutionary processes that drive universal therapeutic resistance in adult patients with
diffuse glioma remain unclear 1 , 2 . Here we analysed temporally separated DNA-…

[HTML][HTML] [18F] flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of …

…, M Zanette, K Heurling, A Chakrabarty, A Ismail… - Alzheimer's & …, 2015 - Elsevier
Background Amyloid positron emission tomography (PET) has become an important tool to
identify amyloid-β (Aβ) pathology in Alzheimer's disease (AD) patients. Here, we determined …

[HTML][HTML] Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection

…, WE Klunk, A Chakrabarty, J Ironside, A Ismail… - Acta neuropathologica …, 2016 - Springer
In vivo imaging of fibrillar β-amyloid deposits may assist clinical diagnosis of Alzheimer’s
disease (AD), aid treatment selection for patients, assist clinical trials of therapeutic drugs …

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

…, LR Bridges, A Chakrabarty, A Ismail… - The lancet child & …, 2020 - thelancet.com
Background Marked variation exists in the use of genomic data in tumour diagnosis, and
optimal integration with conventional diagnostic technology remains uncertain despite several …

Effectiveness of brief alcohol intervention in reducing alcohol consumption among patients with alcohol-related facial trauma in the emergency department; A …

I Azzam, K Lee - Journal of Oral and Maxillofacial Surgery, 2023 - Elsevier
Introduction Facial trauma is a frequent presentation to the emergency department following
alcohol related injuries. Brief alcohol intervention (BAI) is a form of a motivational interview …

[HTML][HTML] Thermal performance of atria: An overview of natural ventilation effective designs

…, N Mahyuddin, N Ab Ghafar, MA Ismail - … and Sustainable Energy …, 2014 - Elsevier
Despite significant impacts of natural ventilation on atria, indoor thermal conditions and
decreasing energy usage load, there is lack of knowledge about how various design parameters …

Atypical teratoid rhabdoid tumour of the spine: report of a case and literature review

…, M Ahmad, A Varghese, T Parekh, A Ismail… - European Spine …, 2015 - Springer
Atypical teratoid rhabdoid tumour (ATRT) is a rare and highly aggressive malignant neoplasm
of the central nervous system (CNS), which occurs predominantly in children less than 2 …

[HTML][HTML] Estimation of amyloid distribution by [18F]flutemetamol PET predicts the neuropathological phase of amyloid β-protein deposition

…, J Lilja, K Heurling, A Chakrabarty, A Ismail… - Acta …, 2018 - Springer
The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological
hallmarks of Alzheimer’s disease (AD). Aβ-plaques arise first in neocortical areas and, then, …

Low-grade spinal glioneuronal tumors with BRAF gene fusion and 1p deletion but without leptomeningeal dissemination

…, JH Harreld, BA Orr, S Sharma, A Ismail… - Acta …, 2017 - Springer
Revised: 21 May 2017/Accepted: 21 May 2017/Published online: 25 May 2017© Springer-Verlag
Berlin Heidelberg 2017 arms 1p and 19q were examined by interphase fluorescence …