User profiles for B Hédan
benoit hedanVerified email at univ-rennes1.fr Cited by 1584 |
FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome
Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the …
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the …
Naturally occurring melanomas in dogs as models for non‐UV pathways of human melanomas
…, M Lagadic, F Galibert, B Hédan… - Pigment cell & …, 2014 - Wiley Online Library
… In this dataset, we further analyzed the distribution per anatomical site for both benign
melanocytic tumors (Figure 1A) and melanomas (Figure 1B). We showed that oral melanoma is …
melanocytic tumors (Figure 1A) and melanomas (Figure 1B). We showed that oral melanoma is …
Epidemiology, pathology, and genetics of histiocytic sarcoma in the Bernese mountain dog breed
Histiocytic sarcoma (HS) refers to a highly aggressive and frequently disseminated neoplastic
disease belonging to the class of canine histiocytic proliferative disorders. Disseminated …
disease belonging to the class of canine histiocytic proliferative disorders. Disseminated …
A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis
…, M Maurer, F Pilot-Storck, B Hédan… - Proceedings of the …, 2010 - National Acad Sciences
Neuronal ceroid lipofuscinoses (NCLs) represent the most common group of inherited
progressive encephalopathies in children. They are characterized by progressive loss of vision, …
progressive encephalopathies in children. They are characterized by progressive loss of vision, …
[HTML][HTML] Canine population structure: assessment and impact of intra-breed stratification on SNP-based association studies
Background In canine genetics, the impact of population structure on whole genome association
studies is typically addressed by sampling approximately equal numbers of cases and …
studies is typically addressed by sampling approximately equal numbers of cases and …
Canine neuropathies: powerful spontaneous models for human hereditary sensory neuropathies
…, L Lagoutte, N Botherel, JL Thibaud, B Hédan… - Human Genetics, 2019 - Springer
… 1b), the left rear paw was first affected and was finally amputated. Six months later, the other
back leg became affected, leading to the euthanasia of the dog. An electroneuromyogram …
back leg became affected, leading to the euthanasia of the dog. An electroneuromyogram …
[HTML][HTML] Identification of common predisposing loci to hematopoietic cancers in four dog breeds
B Hédan, É Cadieu, M Rimbault, A Vaysse… - PLoS …, 2021 - journals.plos.org
… B) Manhattan plot displaying the statistical results from the GWAS. This analysis pointed out
two loci (arrows) on chromosome 11 (CFA11:41161441, p corrected = 3.11 × 10 −7 ) and on …
two loci (arrows) on chromosome 11 (CFA11:41161441, p corrected = 3.11 × 10 −7 ) and on …
[HTML][HTML] Characterisation and functional predictions of canine long non-coding RNAs
…, L Lagoutte, E Cadieu, N Botherel, B Hédan… - Scientific Reports, 2018 - nature.com
Long non-coding RNAs (lncRNAs) are a family of heterogeneous RNAs that play major roles
in multiple biological processes. We recently identified an extended repertoire of more than …
in multiple biological processes. We recently identified an extended repertoire of more than …
Ancestral T-box mutation is present in many, but not all, short-tailed dog breeds
MK Hytönen, A Grall, B Hédan, S Dréano… - Journal of …, 2009 - academic.oup.com
Dogs differ greatly in their morphological characteristics including various tail phenotypes.
Congenitally short-tailed dogs are present in many breeds; however, the causative mutation …
Congenitally short-tailed dogs are present in many breeds; however, the causative mutation …
[HTML][HTML] A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies
…, S Correard, M Paradis, E Guaguère, B Hédan… - PLoS …, 2016 - journals.plos.org
… We used PPIB (Peptidylprolyl Isomerase B) as control and all genes of the locus (GDNF-AS,
GDNF, WDR70, NUP155, SLC1A3) were tested 3 times with 3 replicates for each (t-test: p-…
GDNF, WDR70, NUP155, SLC1A3) were tested 3 times with 3 replicates for each (t-test: p-…