User profiles for B. A. Harley

Brendan Harley

Professor, Chemical & Biomolecular Engineering, University of Illinois at Urbana …
Verified email at illinois.edu
Cited by 12246

Biologically active collagen-based scaffolds: advances in processing and characterization

…, DS Tzeranis, BA Harley… - … Transactions of the …, 2010 - royalsocietypublishing.org
A small number of type I collagen–glycosaminoglycan scaffolds (collagen–GAG scaffolds;
CGSs) have unusual biological activity consisting primarily in inducing partial regeneration of …

The effect of pore size on cell adhesion in collagen-GAG scaffolds

FJ O'Brien, BA Harley, IV Yannas, LJ Gibson - Biomaterials, 2005 - Elsevier
The biological activity of scaffolds used in tissue engineering applications hypothetically
depends on the density of available ligands, scaffold sites at which specific cell binding occurs. …

Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds

FJ O'Brien, BA Harley, IV Yannas, L Gibson - Biomaterials, 2004 - Elsevier
The cellular structure of collagen-glycosaminoglycan (CG) scaffolds used in tissue
engineering must be designed to meet a number of constraints with respect to biocompatibility, …

[BOOK][B] Cellular materials in nature and medicine

LJ Gibson, MF Ashby, BA Harley - 2010 - books.google.com
… Lorna Gibson and Brendan Harley are deeply grateful for the support and patience of
their … Harley also wishes to express his gratitude for the joy that his daughter, Joan Clancy-Harley

Mechanical characterization of collagen–glycosaminoglycan scaffolds

BA Harley, JH Leung, ECCM Silva, LJ Gibson - Acta biomaterialia, 2007 - Elsevier
Tissue engineering scaffolds are used extensively as three-dimensional analogs of the
extracellular matrix (ECM). However, less attention has been paid to characterizing the scaffold …

The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering

FJ O'Brien, BA Harley, MA Waller… - … and Health Care, 2007 - content.iospress.com
The permeability of scaffolds and other three-dimensional constructs used for tissue engineering
applications is important as it controls the diffusion of nutrients in and waste out of the …

A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along osteogenic and chondrogenic routes

…, P Doyle, J Fischer, I Yannas, BA Harley… - Tissue …, 2006 - liebertpub.com
Adult mesenchymal stem cells have the proclivity to differentiate along multiple lineages
giving rise to new bone, cartilage, muscle, or fat. Collagen, a normal constituent of bone, …

Design of a multiphase osteochondral scaffold III: Fabrication of layered scaffolds with continuous interfaces

BA Harley, AK Lynn, Z Wissner‐Gross… - … Research Part A: An …, 2010 - Wiley Online Library
There is a need to improve current treatments for articular cartilage injuries. This article is the
third in a series describing the design and development of an osteochondral scaffold based …

Design of a multiphase osteochondral scaffold. II. Fabrication of a mineralized collagen–glycosaminoglycan scaffold

BA Harley, AK Lynn, Z Wissner‐Gross… - … Research Part A: An …, 2010 - Wiley Online Library
This paper is the second in a series of papers describing the design and development of an
osteochondral scaffold using collagen–glycosaminoglycan and calcium phosphate …

Fabricating tubular scaffolds with a radial pore size gradient by a spinning technique

BA Harley, AZ Hastings, IV Yannas, A Sannino - Biomaterials, 2006 - Elsevier
A novel fabrication process has been developed to produce collagen-based, porous tubular
scaffolds to facilitate the study of myofibroblast migration during peripheral nerve …