Both virus and tumor necrosis factor alpha are critical for endothelium damage in a mouse model of dengue virus-induced hemorrhage

…, FM Hofman, JT Kung, YD Lin, BA Wu-Hsieh - Journal of …, 2007 - Am Soc Microbiol
Hemorrhage is a common clinical manifestation in dengue patients. However, the pathogenic
mechanism of dengue virus (DV)-induced hemorrhage awaits clarification. We established …

Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus

…, JP Chen, JM Sung, YL Lin, BA Wu-Hsieh… - The Journal of …, 2006 - journals.aai.org
We examined the extent to which CXCR3 mediates resistance to dengue infection. Following
intracerebral infection with dengue virus, CXCR3-deficient (CXCR3−/−) mice showed …

Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro

…, CH Hsiao, CL Kao, YC Chen, BA Wu-Hsieh - Journal of …, 2006 - Am Soc Microbiol
The clinical picture of severe acute respiratory syndrome (SARS) is characterized by
pulmonary inflammation and respiratory failure, resembling that of acute respiratory distress …

Enhancement by tumor necrosis factor alpha of dengue virus-induced endothelial cell production of reactive nitrogen and oxygen species is key to hemorrhage …

…, HC Chen, YD Lin, CC Shieh, BA Wu-Hsieh - Journal of …, 2008 - Am Soc Microbiol
Hemorrhage is a severe manifestation of dengue disease. Virus strain and host immune
response have been implicated as the risk factors for hemorrhage development. To delineate …

SARS-CoV regulates immune function-related gene expression in human monocytic cells

W Hu, YT Yen, S Singh, CL Kao, BA Wu-Hsieh - Viral immunology, 2012 - liebertpub.com
… 64 Yen YTLiao FHsiao CHKao CLChen YCWu-Hsieh BAModeling the early events of severe
… Yen YT, Liao F, Hsiao CH, Kao CL, Chen YC, and Wu-Hsieh BA: Modeling the early events …

[HTML][HTML] CR3 and dectin-1 collaborate in macrophage cytokine response through association on lipid rafts and activation of Syk-JNK-AP-1 pathway

…, CL Chu, GD Brown, CP Chuu, BA Wu-Hsieh - PLoS …, 2015 - journals.plos.org
Collaboration between heterogeneous pattern recognition receptors (PRRs) leading to
synergistic coordination of immune response is important for the host to fight against invading …

[HTML][HTML] Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2

…, HW Kan, ST Hsieh, FT Liu, BA Wu-Hsieh - PLoS …, 2019 - journals.plos.org
Candida albicans is one of the top leading causes of healthcare-associated bloodstream
infection. Neutrophil extracellular traps (NET) are known to capture and kill pathogens. It is …

Dengue virus induces expression of CXC chemokine ligand 10/IFN-γ-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate

…, JM Sung, MY Lu, BA Wu-Hsieh… - The Journal of …, 2006 - journals.aai.org
Dengue virus is an arthropod-borne flavivirus that causes a mild febrile illness, dengue fever,
or a potentially fatal syndrome, dengue hemorrhagic fever/dengue shock syndrome. …

[HTML][HTML] Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1

…, R Anderson, HS Liu, TM Yeh, YT Yen, BA Wu-Hsieh… - PLoS …, 2014 - journals.plos.org
Background Infection with dengue virus (DENV) may cause life-threatening disease with
thrombocytopenia and vascular leakage which are related to dysfunction of platelets and …

Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17–axis cytokines in infection by Histoplasma capsulatum

…, JS Yu, FT Liu, SC Miaw, BA Wu-Hsieh - The Journal of …, 2013 - journals.aai.org
Galectin-3 (gal3) is known for its immunoregulatory functions in infectious, autoimmune, and
inflammatory diseases. However, little is known about its regulatory role in the host's IL-17A …