Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection
Spontaneous intracranial artery dissection is an uncommon and probably underdiagnosed
cause of stroke that is defined by the occurrence of a haematoma in the wall of an intracranial …
cause of stroke that is defined by the occurrence of a haematoma in the wall of an intracranial …
Endovascular vs medical management of acute ischemic stroke
…, RW Crowley, KC Liu, AM Southerland, BB Worrall - Neurology, 2015 - AAN Enterprises
… Worrall: data interpretation, critical revision of the manuscript for important intellectual content,
… Worrall serves as associate editor of Neurology®. Go to Neurology.org for full disclosures. …
… Worrall serves as associate editor of Neurology®. Go to Neurology.org for full disclosures. …
Genetically determined levels of circulating cytokines and risk of stroke: role of monocyte chemoattractant protein-1
…, JM Lee, Y Kamatani, JC Hopewell, BB Worrall… - Circulation, 2019 - Am Heart Assoc
Background: Cytokines and growth factors have been implicated in the initiation and propagation
of vascular disease. Observational studies have shown associations of their circulating …
of vascular disease. Observational studies have shown associations of their circulating …
[HTML][HTML] Early-onset stroke and vasculopathy associated with mutations in ADA2
…, A Jones, JF Meschia, BB Worrall… - … England Journal of …, 2014 - Mass Medical Soc
Background We observed a syndrome of intermittent fevers, early-onset lacunar strokes and
other neurovascular manifestations, livedoid rash, hepatosplenomegaly, and systemic …
other neurovascular manifestations, livedoid rash, hepatosplenomegaly, and systemic …
[HTML][HTML] Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
…, S Yadav, EA Parati, AL DeStefano, BB Worrall… - The Lancet …, 2012 - thelancet.com
Background Various genome-wide association studies (GWAS) have been done in ischaemic
stroke, identifying a few loci associated with the disease, but sample sizes have been …
stroke, identifying a few loci associated with the disease, but sample sizes have been …
Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
…, AC Viswanathan, NW Wood, BB Worrall… - Nature …, 2012 - nature.com
Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
[HTML][HTML] Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic …
…, AB Singleton, L Ferrucci, J Hardy, BB Worrall… - The Lancet, 2011 - thelancet.com
Background The MTHFR 677C→T polymorphism has been associated with raised homocysteine
concentration and increased risk of stroke. A previous overview showed that the effects …
concentration and increased risk of stroke. A previous overview showed that the effects …
Causal associations of adiposity and body fat distribution with coronary heart disease, stroke subtypes, and type 2 diabetes mellitus: a Mendelian randomization …
…, R Noordam, MJ Caulfield, JW Jukema, BB Worrall… - Circulation, 2017 - Am Heart Assoc
Background: The implications of different adiposity measures on cardiovascular disease
etiology remain unclear. In this article, we quantify and contrast causal associations of central …
etiology remain unclear. In this article, we quantify and contrast causal associations of central …
[HTML][HTML] Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N= 112 151) and 24 GWAS consortia
Causes of the well-documented association between low levels of cognitive functioning and
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …
many adverse neuropsychiatric outcomes, poorer physical health and earlier death remain …