Cytoskeletal molecular motors belonging to the kinesin and dynein families transport cargos
(for example, messenger RNA, endosomes, virus) on polymerized linear structures called …

Motor-based intracellular transport and its regulation are crucial to the functioning of a cell.
Disruption of transport is linked to Alzheimer's and other neurodegenerative diseases. …

We measured the time course of sodium entry during action potentials of mouse central
neurons at 37C to examine how efficiently sodium entry is coupled to depolarization. In cortical …

Transient receptor potential melastatin-like 7 (TRPM7) is a channel protein that also contains
a regulatory serine-threonine kinase domain. Here, we find that Trpm7 −/− T cells are …

As our knowledge of biological processes advances, we are increasingly aware that cells
actively position sub-cellular organelles and other constituents to control a wide range of …

… Unlike Carter and Cross, we calculate the probability of observing a particular t-value for
a given degree of freedom (P(t,df), calculated using the built-in LabVIEW function) with the …

Tetrodotoxin (TTX)-sensitive sodium channels carry large transient currents during action
potentials and also "persistent" sodium current, a noninactivating TTX-sensitive current present …

Advanced prostate cancers resistant to androgen receptor antagonists are still susceptible
to nontoxic BRD9 inhibitors, making them a promising alternative for halting AR signaling in …

INTRODUCTION: Endoscopic cyclophotocoagulation (ECP) has been shown to be a useful
adjunct in the management of a variety of difficult pediatric and adult glaucomas. This study …

Long-term depression (LTD) between cortical layer 4 spiny stellate cells and layer 2/3 pyramidal
cells requires the activation of NMDA receptors (NMDARs). In young rodents, this form …