Basement membranes (BMs) are thin sheet-like specialized extracellular matrices found at
the basal surface of epithelia and endothelial tissues. They have been conserved across …

Drosophila melanogaster plasmatocytes, the phagocytic cells among hemocytes, are essential
for immune responses, but also play key roles from early development to death through …

In this study, we found that in the adipose tissue of wildtype animals, insulin and TGF‐β
signalling converge via a BMP antagonist short gastrulation (sog) to regulate ECM remodelling. …

Throughout embryonic development, macrophages not only act as the first line of defence
against infection but also help to sculpt organs and tissues of the embryo by removing dead …

Forces controlling tissue morphogenesis are attributed to cellular-driven activities, and any
role for extracellular matrix (ECM) is assumed to be passive. However, all polymer networks, …

The basement membrane (BM) is a thin layer of extracellular matrix (ECM) beneath nearly
all epithelial cell types that is critical for cellular and tissue function. It is composed of …

… In contrast, using the fruit fly, Sanchez Sanchez et al. show that Drosophila embryonic
hemocytes use autocrineproduced laminins to regulate lamellipodia stability, dynamics, and …

… Using modeling and in vivo pulse-chase experiments, Matsubayashi, Sanchez -Sanchez
et al. show that the embryonic fruit fly ECM has a surprisingly short half-life. This labile ECM …

The forces controlling tissue morphogenesis are attributed to cellular-driven activities and
any role for extracellular matrix (ECM) is assumed to be passive. However, all polymer …

Protein turnover rate is difficult to obtain experimentally. This protocol shows how to
mathematically model turnover rates in an intervention-free manner given the ability to quantify …