… Inside the cell, fructose is phosphorylated to fructose-1-phosphate by fructokinase and
then subsequently cleaved by aldolase B to form glyceraldehyde and dihydroxyacetone …

… Chief amongst the risks of HCC are hepatitis B and C infection, aflatoxin B1 ingestion,
alcoholism and obesity. The latter can promote non-alcoholic fatty liver disease (NAFLD), that can …

The immature physiology of cardiomyocytes derived from human induced pluripotent stem
cells (hiPSCs) limits their utility for drug screening and disease modelling. Here we show that …

Rapid nucleic acid testing is central to infectious disease surveillance. Here, we report an
assay for rapid COVID-19 testing and its implementation in a prototype microfluidic device. The …

… b Details of the microfluidic features including media inlet (IN) and outlet (OUT) as well as
the cell loading port (cell in), cell chamber with anchor pillars, media channels, and connecting …

… Using this model of hiPSC-CMs, we then define a maturation matrix Q such that Qp hiPSC,C
= p A,B , where p A,B (A is for adult, B is for base) are known parameters representing a …

… parameter vector p IM,B , representing a prototypical IM cell, and an associated base
maturation map Q B . The associated M cells are characterized by p M = Q B p IM,B . The M model, …

Despite global efforts, it took 7 months between the proclamation of global SARS-CoV-2
pandemic and the first FDA-approved treatment for COVID-19. During this timeframe, clinicians …

Adiponectin demonstrates beneficial effects in various metabolic diseases, including diabetes,
and in bowel cancer. Recent data also suggest a protective role in colitis. However, the …

… (B) Phase contrast images of the MPS with cardiac tissues formed using WTC (top) and
SCVI20 (bottom) cells. Scale bars represent 100 μm. (C) Fluorescent voltage traces (black and …