User profiles for B. Liffner
Benjamin LiffnerIndiana University School of Medicine Verified email at iu.edu Cited by 278 |
[HTML][HTML] The dynamic roles of the inner membrane complex in the multiple stages of the malaria parasite
Apicomplexan parasites, such as human malaria parasites, have complex lifecycles encompassing
multiple and diverse environmental niches. Invading, replicating, and escaping from …
multiple and diverse environmental niches. Invading, replicating, and escaping from …
Expansion microscopy of apicomplexan parasites
… for harvesting malaria parasites at multiple timepoints/ lifecycle stages (Liffner & Absalon,
2021), along with the testing of a wide number of marker antibodies and chemical dyes (Liffner …
2021), along with the testing of a wide number of marker antibodies and chemical dyes (Liffner …
Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
… (b) U- ExM workflow used in this study. PFA = paraformaldehyde, FA = formaldehyde, AA =
acrylamide, PG = propyl gallate. Snowflake indicates steps where gels were cryopreserved. …
acrylamide, PG = propyl gallate. Snowflake indicates steps where gels were cryopreserved. …
[HTML][HTML] Expansion Microscopy Reveals Plasmodium falciparum Blood-Stage Parasites Undergo Anaphase with A Chromatin Bridge in the Absence of Mini …
… Given that each of the microtubule structures could be distinguished from each other
using U-ExM (Figure 1b), we used this technique to study microtubule formation in MCMBP-…
using U-ExM (Figure 1b), we used this technique to study microtubule formation in MCMBP-…
Dissecting the gene expression, localization, membrane topology, and function of the Plasmodium falciparum STEVOR protein family
… (B) Line plot showing smoothed conditional means of log 2 FPKM stevor gene expression
values as calculated with the LOESS smoothing method, including their 0.95 confidence …
values as calculated with the LOESS smoothing method, including their 0.95 confidence …
[HTML][HTML] PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes
… b The amino acid sequence of PfCERLI1 was compared against Plasmodium spp. … that
amplify only WT Pfcerli1 locus (primer A and B) or primers that amplify only integrated Pfcerli1 …
amplify only WT Pfcerli1 locus (primer A and B) or primers that amplify only integrated Pfcerli1 …
The ins and outs of Plasmodium rhoptries, focusing on the cytosolic side
B Liffner, JM Balbin, JS Wichers, TW Gilberger… - Trends in …, 2021 - cell.com
Parasites of the genus Plasmodium cause human and animal malaria, leading to significant
health and economic impacts. A key aspect of the complex life cycle of Plasmodium …
health and economic impacts. A key aspect of the complex life cycle of Plasmodium …
[PDF][PDF] Structure-based identification and functional characterization of a lipocalin in the malaria parasite Plasmodium falciparum
…, K Lauk, A Zurborg, C Soehnchen, B Liffner… - Cell Reports, 2020 - cell.com
… The overall monomeric structure of PfLCN reveals the classic lipocalin fold with a b-barrel
calyx core consisting of eight hydrogen-bonded anti-parallel b strands and an N-terminal a he…
calyx core consisting of eight hydrogen-bonded anti-parallel b strands and an N-terminal a he…
[HTML][HTML] Retargeting azithromycin analogues to have dual-modality antimalarial activity
… b Schematic of drug washout treatment scheme to assess azithromycin’s quick-killing
stage of activity. Early ring-stage parasites (0–4 hrs post-invasion) were aliquoted to a 96-well …
stage of activity. Early ring-stage parasites (0–4 hrs post-invasion) were aliquoted to a 96-well …
Structural insights into PfARO and characterization of its interaction with PfAIP
… Arrows (P1–P4) are indicating position of oligonucleotides used for B. (B) PCR analysis of
the rendered genomic locus using primers as shown in the schema using gDNA of 3D7 wild …
the rendered genomic locus using primers as shown in the schema using gDNA of 3D7 wild …