… Following a host shift, selection will favour mutations that allow a pathogen to (a) enter a
host cell with greater efficiency and (b) “fine tune” or optimise their fitness in the new host, for …

This article reviews research on the evolutionary mechanisms leading to different transmission
modes. Such modes are often under genetic control of the host or the pathogen, and …

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae
and Sunviridae), the elevation of the paramyxoviral subfamily …

Globally, Hepatitis E virus (HEV) causes over 20 million cases worldwide. HEV is an emerging
and endemic pathogen within economically developed countries, chiefly resulting from …

Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

The family Rhabdoviridae comprises viruses with negative-sense (–) single-stranded RNA
genomes of 10.8–16.1 kb. Virions are typically enveloped with bullet-shaped or bacilliform …

… The phylogeny reveals that 18 of the strains clustered in what is commonly regarded as the
supergroup A [66], with wMa being the only strain from the supergroup B (Figure 1A). Many …

… If we imagine two sister species (A and B) and an out-group (… more different to that in C than
B. Importantly, however, we do … increases as we move to species B and then to species C, or …

Variation in susceptibility to infectious disease often has a substantial genetic component in
animal and plant populations. We have used genome-wide association studies (GWAS) in …

… Viral load is the change in viral load between day 0 and day 2 post infection (see Figure B
in S1 Text for data at each time point). D. melanogaster, the species DCV was isolated from, is …